Clinical and morphological features, immune profile of renal cell tumors with clear cytoplasm

被引：0
|
作者：
Osmanov, Yu. I. [1 ,2 ]
Kogan, E. A. [1 ]
Severgina, L. O. [1 ]
Rapoport, L. M. [3 ]
Aleksandrov, N. S. [1 ]
Tsarichenko, D. G. [3 ]
Korolyov, D. O. [3 ]
机构：
[1] Sechenov First Moscow State Med Univ, Minist Hlth Russia, Anat Pathol Dept, Build 2,8 Trubetskaya St, Moscow 119991, Russia
[2] Russian Railway, Sci Clin Ctr, Dept Pathol, 84 Volokolamskoe Shosse, Moscow 125367, Russia
[3] Sechenov First Moscow State Med Univ, Minist Hlth Russia, Inst Urol & Reprod Hlth, Build 1,2 Bolshaya Pirogovskaya St, Moscow 119435, Russia
来源：
ONKOUROLOGIYA | 2019年 / 15卷 / 03期
关键词：
renal cell carcinoma; renal tumors; immunohistochemical diagnosis; IMMUNOHISTOCHEMICAL ANALYSIS; DIFFERENTIAL-DIAGNOSIS; STROMAL TUMOR; CARCINOMA; NEOPLASMS; KIDNEY; GENE; ANGIOMYOLIPOMA; ONCOCYTOMA; CLASSIFICATION;
D O I：
10.17650/1726-9776-2019-15-3-126-131
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In the structure of ontological morbidity, renal cell carcinoma takes the 10th place among malignant neoplasms. The increase in incidence is observed from the age of 35-40 years and reaches a maximum at the age of 65-70 years. In terms of frequency of occurrence, clear cell renal cell carcinoma is ranked first among all kidney tumors. Meanwhile, due to the high heterogeneity of renal cell carcinomas with clear cytoplasm group, significant differential diagnostic difficulties arise in the morphological verification of these tumors. The article presents all nasological forms of kidney tumors with clear cytoplasm and provides a database of already known immunohistochemical markers for each nosological unit.
引用
收藏
页码：126 / 131
页数：6
相关论文
共 50 条
  • [21] Immune classification of clear cell renal cell carcinoma
    Sumeyye Su
    Shaya Akbarinejad
    Leili Shahriyari
    Scientific Reports, 11
  • [22] Renal Cell Carcinoma With Clear Cell and Papillary Features
    Ross, Hillary
    Martignoni, Guido
    Argani, Pedram
    ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2012, 136 (04) : 391 - 399
  • [23] Clinical outcomes of checkpoint inhibitors in metastatic non-clear cell renal cell carcinoma and clear cell renal cell carcinoma with variant features.
    Chang, Guy vin
    Ellithi, Moataz
    Elnair, Radowan
    Bleeker, Jonathan
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [24] The renal clear cell carcinoma immune landscape
    Saad, Omar A.
    Li, Wei Tse
    Krishnan, Aswini R.
    Nguyen, Griffith C.
    Lopez, Jay P.
    McKay, Rana R.
    Wang-Rodriguez, Jessica
    Ongkeko, Weg M.
    NEOPLASIA, 2022, 24 (02): : 145 - 154
  • [25] Eosinophilic features in clear cell renal cell carcinoma correlate with outcomes of immune checkpoint and angiogenesis blockade
    Yoshida, Takashi
    Ohe, Chisato
    Ikeda, Junichi
    Atsumi, Naho
    Ohsugi, Haruyuki
    Sugi, Motohiko
    Higasa, Koichiro
    Saito, Ryoichi
    Tsuta, Koji
    Matsuda, Tadashi
    Kinoshita, Hidefumi
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 (09)
  • [26] CLINICAL FEATURES OF RECURRENT SOMATIC MUTATIONS IN CLEAR CELL RENAL CELL CARCINOMA: A LARGE COHORT
    Manley, Brandon J.
    Casuscelli, Jozefina
    Tennenbaum, Daniel M.
    Becerra, Maria F.
    Redzematovic, Almedina
    Arcila, Maria E.
    Voss, Martin H.
    Feldman, Darren R.
    Coleman, Jonathan A.
    Russo, Paul
    Motzer, Robert J.
    Hsieh, James J.
    Hakimi, A. Ari
    JOURNAL OF UROLOGY, 2016, 195 (04): : E919 - E919
  • [27] Clinical and Morphological Features of Fumarate Hydratase Deficient Testicular Leydig Cell Tumors
    Kim, Roger
    Mitchell, Catherine
    Fellowes, Andrew
    Perry-Keene, Joanna
    Swarbrick, Nicole
    Gill, Anthony
    Maclean, Fiona
    Fuchs, Talia
    LABORATORY INVESTIGATION, 2024, 104 (03) : S971 - S973
  • [28] The Clinical and Molecular Features in the VHL Renal Cancers; Close or Distant Relatives with Sporadic Clear Cell Renal Cell Carcinoma?
    Cinque, Alessandra
    Minnei, Roberto
    Floris, Matteo
    Trevisani, Francesco
    CANCERS, 2022, 14 (21)
  • [29] The Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
    Monjaras-Avila, Cesar U.
    Lorenzo-Leal, Ana C.
    Luque-Badillo, Ana C.
    D'Costa, Ninadh
    Chavez-Munoz, Claudia
    Bach, Horacio
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (09)
  • [30] DNA Methylation Profile Distinguishes Clear Cell Sarcoma of the Kidney from Other Pediatric Renal Tumors
    Ueno, Hitomi
    Okita, Hajime
    Akimoto, Shingo
    Kobayashi, Kenichiro
    Nakabayashi, Kazuhiko
    Hata, Kenichiro
    Fujimoto, Junichiro
    Hata, Jun-ichi
    Fukuzawa, Masahiro
    Kiyokawa, Nobutaka
    PLOS ONE, 2013, 8 (04):
12345