Synthesis and antifungal activity of novel 2,5-disubstituted-1,3,4-oxadiazoles containing benzimidazole moiety

被引：5
|
作者：
Zhang, Zeyuan [1 ]
Mu, Wei [2 ]
Ji, Zengchen [2 ]
Jiang, Lin [1 ]
机构：
[1] Shandong Agr Univ, Coll Chem & Mat Sci, Tai An 271018, Shandong, Peoples R China
[2] Shandong Agr Univ, Coll Plant Protect, Tai An 271018, Shandong, Peoples R China
来源：
JOURNAL OF PESTICIDE SCIENCE | 2012年 / 37卷 / 04期
关键词：
1,3,4-oxadiazole; benzimidazole; synthesis; antifungal activity; 1,3,4-OXADIAZOLE DERIVATIVES; BIOLOGICAL EVALUATION; AGENTS; DESIGN; ACID;
D O I：
10.1584/jpestics.D12-040
中图分类号：
Q96 [昆虫学];
学科分类号：
摘要：
Eighteen novel compounds of 2,5-disubstituted-1,3,4-oxadiazoles containing benzimidazole moiety were synthesized from 1H-benzimidazole-2-carbohydrazide, carbon disulfide and alkyl halide or benzyl halide by multi-step reactions. The structures of the target compounds were confirmed by IR, H-1-NMR spectra and elemental analyses. Preliminary antifungal activities against Botrytis cinerea and Sclerotinia sclerotiorum were also evaluated by the mycelium growth rate method, and the results indicated that many target compounds possess excellent antifungal activity, even higher than the control fungicide (carbendazim). (C) Pesticide Science Society of Japan
引用
收藏
页码：338 / 341
页数：4
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