Spin-echo planar spectroscopic imaging for fast lipid characterization in bone marrow

被引：8
|
作者：
Bao, S [1 ]
Guttmann, CGR [1 ]
Mugler, JP [1 ]
Brookeman, JR [1 ]
Panych, LP [1 ]
Kraft, RA [1 ]
Oshio, K [1 ]
Jaramillo, D [1 ]
Jolesz, FA [1 ]
Williamson, DS [1 ]
Mulkern, RV [1 ]
机构：
[1] Harvard Univ, Sch Med, Childrens Hosp, Dept Radiol, Boston, MA 02115 USA
来源：
MAGNETIC RESONANCE IMAGING | 1999年 / 17卷 / 08期
关键词：
lipids; H-1; MRS; echo planar imaging (EPI);
D O I：
10.1016/S0730-725X(99)00056-9
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Lipid characterization of bone marrow in vivo with proton magnetic resonance spectroscopy was performed using Spin-Echo Planar Spectroscopic Imaging sequences. The methods are shown capable of rapidly generating two-dimensional chemical shift imaging data sets suitable for measuring lipid indices that reflect unsaturation levels among triglycerides, as demonstrated in oil phantoms and bone marrow from a healthy volunteer. The volume coverage, spatial resolution, acquisition speed; and spectral characteristics of Spin-Echo Planar Spectroscopic Imaging should make it attractive for clinical studies of diseases affecting normal lipid chemical composition. (C) 1999 Elsevier Science Inc.
引用
收藏
页码：1203 / 1210
页数：8
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