PI3Kδ and PI3Kγ as Targets for Autoimmune and Inflammatory Diseases

被引：77
|
作者：
Cushing, Timothy D. [1 ]
Metz, Daniela P. [2 ]
Whittington, Douglas A. [3 ]
McGee, Lawrence R. [1 ]
机构：
[1] Amgen Inc, Therapeut Discovery, 1120 Vet Blvd, San Francisco, CA 94080 USA
[2] Amgen Inc, Inflammat Res, Thousand Oaks, CA 91320 USA
[3] Amgen Inc, Mol Struct & Characterizat, Cambridge, MA 02142 USA
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2012年 / 55卷 / 20期
关键词：
PHOSPHOINOSITIDE 3-KINASE GAMMA; PI3; KINASE; NEUTROPHIL TRAFFICKING; AIRWAY INFLAMMATION; SYSTEMIC-LUPUS; CLASS IA; B-CELL; INHIBITION; P110-DELTA; ISOFORM;
D O I：
10.1021/jm300847w
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：8559 / 8581
页数：23
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