The Biological Role of Carnosine and Its Possible Applications in Medicine

被引:1
|
作者
Budzen, Sandra [1 ]
Rymaszewska, Joanna [2 ]
机构
[1] Wroclaw Phys Educ Acad, Dept Physiotherapy, Wroclaw, Poland
[2] Wroclaw Med Univ, Dept Psychiat, Res Unit Consultat Liaison Psychiat & Behav Me, Wroclaw, Poland
来源
关键词
carnosine; antioxidant effect; dementia; somatic diseases; dietary supplementation; BETA-ALANINE SUPPLEMENTATION; MUSCLE CARNOSINE; EXERCISE; THERAPY; DAMAGE;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The article reviews current literature on the biological role of carnosine, its properties and use as a supplement in periods of intense physical activity. Studies carried out on laboratory animals and humans have shown that carnosine can have a beneficial influence on the organism. Carnosine is found naturally mainly in the skeletal muscles, central nervous system, olfactory neurons and in the lens of the eye in some vertebrates, including humans. Due to its antioxidant, protective, chelating, anti-glycation activity, this dipeptide can be used to prevent and treat diseases such as diabetes, neurodegenerative diseases, diseases of the sense organs and cancers. It may also cure or alleviate many other disorders thanks to its wide spectrum of activity. Carnosine is already used by athletes to achieve better results, due to its buffering feature, which contributes to the maintenance of the acid-base balance in the muscles. Future studies on the influence of carnosine on the human organism may lead to the therapeutic use of this dipeptide for many diseases, in addition to improving both amateur and professional athletes' results
引用
下载
收藏
页码:739 / 744
页数:6
相关论文
共 50 条
  • [41] POSSIBLE BIOLOGICAL EFFECTS AND DANGERS OF ULTRASOUNDS IN PERINATAL MEDICINE
    RELIER, JP
    PERRIN, J
    ARCHIVES FRANCAISES DE PEDIATRIE, 1985, 42 (07): : 491 - 495
  • [42] Biological therapy for rheumatoid arthritis: is personalised medicine possible?
    Callaghan, C. A.
    Boyter, A. C.
    Mullen, A. B.
    McRorie, E. R.
    EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE, 2014, 21 (04): : 229 - 237
  • [43] The role of carnosine in CNS
    Chen, Zhong
    Fan, Yanying
    Zhang, Jianxiang
    He, Ping
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, 109 : 116P - 116P
  • [44] The role of mesenchymal stromal cells in spinal cord injury, regenerative medicine and possible clinical applications
    Forostyak, Serhiy
    Jendelova, Pavla
    Sykova, Eva
    BIOCHIMIE, 2013, 95 (12) : 2257 - 2270
  • [45] The role of carnosine in CNS
    Yan-Yin, Fan
    Jian-Xiang, Zhang
    Ping, He
    Zhong, Chen
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, 109 : 272P - 272P
  • [46] COMPLEMENT ACTIVATION BY HOUSE DUST - ITS BIOLOGICAL CONSEQUENCES AND POSSIBLE ROLE IN RESPIRATION PATHOLOGY
    RADERMECKER, M
    MALDAGUE, MP
    GUSTIN, M
    SAINTREMY, P
    REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE, 1982, 22 (03): : 133 - 139
  • [47] BIOLOGICAL PROPERTIES OF EPSTEIN-BARR VIRUS AND ITS POSSIBLE ROLE IN HUMAN MALIGNANCY
    GLASER, R
    RAPP, F
    PROGRESS IN MEDICAL VIROLOGY, 1975, 21 : 43 - 57
  • [48] Uncoupling Protein 3: Its Possible Biological Role and Mode of Regulation in Rodents and Humans
    Patrick Muzzin
    Olivier Boss
    Jean-Paul Giacobino
    Journal of Bioenergetics and Biomembranes, 1999, 31 : 467 - 473
  • [49] Uncoupling protein 3: Its possible biological role and mode of regulation in rodents and humans
    Muzzin, P
    Boss, O
    Giacobino, JP
    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 1999, 31 (05) : 467 - 473
  • [50] POLAROGRAPHY AND ITS BIOLOGICAL APPLICATIONS
    SILVER, IA
    PHYSICS IN MEDICINE AND BIOLOGY, 1967, 12 (03): : 285 - &