Effective methods to improve the biocompatibility of poly (dimethylsiloxane)

被引：0

作者：

Park, Joong Yull ^{[1
]}

Hwang, Chang Mo ^{[1
,2
]}

Lee, Sang-Hoon ^{[1
]}

机构：

[1] Korea Univ, Coll Med, Dept Biomed Engn, Seoul 136705, South Korea

[2] Korea Univ, Korea Artificial Organ Ctr, Seoul 136705, South Korea

来源：

BIOCHIP JOURNAL | 2008年 / 2卷 / 01期

关键词：

biocompatibility; PDMS; microfluidic chip; fibroblast;

D O I：

暂无

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Poly (dimethylsiloxane) (Pi has become one of the popular materials in the field of bio-related microfluidic systems, and has been used for various biological assays. While the material is known to be biocompatible in general, it also has been reported that the attachment and survival rate of cells are limited on a Pi substrate. In this paper, a simple and relevant method to improve the biocompatibility of Pi is proposed; the effects of various treatments using ethanol, water, and boiling-water were evaluated. The results show that the boiling-water treatment is the most appropriate, time saving, and simple method to improve the biocompatibility of Pi

引用

页码：39 / 43

页数：5

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