Effective methods to improve the biocompatibility of poly (dimethylsiloxane)

被引：0
|
作者：
Park, Joong Yull [1 ]
Hwang, Chang Mo [1 ,2 ]
Lee, Sang-Hoon [1 ]
机构：
[1] Korea Univ, Coll Med, Dept Biomed Engn, Seoul 136705, South Korea
[2] Korea Univ, Korea Artificial Organ Ctr, Seoul 136705, South Korea
来源：
BIOCHIP JOURNAL | 2008年 / 2卷 / 01期
关键词：
biocompatibility; PDMS; microfluidic chip; fibroblast;
D O I：
暂无
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Poly (dimethylsiloxane) (Pi has become one of the popular materials in the field of bio-related microfluidic systems, and has been used for various biological assays. While the material is known to be biocompatible in general, it also has been reported that the attachment and survival rate of cells are limited on a Pi substrate. In this paper, a simple and relevant method to improve the biocompatibility of Pi is proposed; the effects of various treatments using ethanol, water, and boiling-water were evaluated. The results show that the boiling-water treatment is the most appropriate, time saving, and simple method to improve the biocompatibility of Pi
引用
收藏
页码：39 / 43
页数：5
相关论文
共 50 条
  • [1] Biocompatibility properties of surface-modified poly(dimethylsiloxane) for urinary applications
    Lippens, Evi
    De Smet, Nele
    Schauvliege, Stijn
    Martens, Ann
    Gasthuys, Frank
    Schacht, Etienne
    Cornelissen, Ria
    JOURNAL OF BIOMATERIALS APPLICATIONS, 2013, 27 (06) : 651 - 660
  • [2] Structure and properties of thermoplastic polyurethanes based on poly(dimethylsiloxane): Assessment of biocompatibility
    Pergal, Marija V.
    Nestorov, Jelena
    Tovilovic, Gordana
    Ostojic, Sanja
    Godevac, Dejan
    Vasiljevic-Radovic, Dana
    Djonlagic, Jasna
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2014, 102 (11) : 3951 - 3964
  • [3] The biocompatibility and hydrophilicity evaluation of collagen grafted poly(dimethylsiloxane) and poly (2-hydroxyethylmethacrylate) blends
    Rezaei, Seyed Mahmood
    Ishak, Z. A. Mohd
    POLYMER TESTING, 2011, 30 (01) : 69 - 75
  • [4] Effective PEGylation method to improve biocompatibility of graphene derivatives
    Demirel, Erhan
    Karaca, Ezgi
    Durmaz, Yasemin Yuksel
    EUROPEAN POLYMER JOURNAL, 2020, 124
  • [5] Enhanced Biocompatibility and Differentiation Capacity of Mesenchymal Stem Cells on Poly(dimethylsiloxane) by Topographically Patterned Dopamine
    Hung, Huey-Shan
    Yu, Alex Yang-Hao
    Hsieh, Shu-Chen
    Kung, Mei-Lang
    Huang, Hsiu-Yuan
    Fu, Ru-Huei
    Yeh, Chun-An
    Hsu, Shan-Hui
    ACS APPLIED MATERIALS & INTERFACES, 2020, 12 (40) : 44393 - 44406
  • [6] Hydrophilic Modification Strategies to Enhance the Surface Biocompatibility of Poly(dimethylsiloxane)-Based Biomaterials for Medical Applications
    Sutthiwanjampa, Chanutchamon
    Hong, Seungpyo
    Kim, Woo Ju
    Kang, Shin Hyuk
    Park, Hansoo
    ADVANCED MATERIALS INTERFACES, 2023, 10 (12)
  • [7] DIPOLE MOMENTS OF DIMETHYLSILOXANE OLIGOMERS AND POLY(DIMETHYLSILOXANE)
    SUTTON, C
    MARK, JE
    JOURNAL OF CHEMICAL PHYSICS, 1971, 54 (12): : 5011 - &
  • [8] Formulation Prediction for Young's Modulus of Poly(dimethylsiloxane) by Spectroscopic Methods
    Cho, Han Saem
    Moon, Heh-Young
    Lee, Heung Soon
    Kim, Yong Tae
    Jeoung, Sae Chae
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2021, 42 (09) : 1225 - 1231
  • [9] THERMODYNAMICS OF SOLUTIONS OF POLY(DIMETHYLSILOXANE) .2. SOLUTION OF POLY(DIMETHYLSILOXANE) IN OCTAMETHYLCYCLOTETRASILOXANE
    SHIOMI, T
    KOHRA, Y
    HAMADA, F
    NAKAJIMA, A
    MACROMOLECULES, 1980, 13 (05) : 1154 - 1156
  • [10] Poly(dimethylsilylenemethylene-co-dimethylsiloxane):: A regularly alternating copolymer of poly(dimethylsiloxane) and poly(dimethylsilylenemethylene)
    Interrante, LV
    Shen, QH
    Li, J
    MACROMOLECULES, 2001, 34 (06) : 1545 - 1547
12345