Medulloblastoma in a Child with Fragile X Syndrome

被引：2

作者：

Alexiou, George A. ^{[1
]}

Siozos, George ^{[2
]}

Stefanaki, Kalliopi ^{[2
]}

Vlachakis, Eustathios ^{[1
]}

Sfakianos, George ^{[1
]}

Prodromou, Neofytos ^{[1
]}

Moschovi, Maria ^{[3
]}

机构：

[1] Childrens Hosp Agia Sofia, Dept Neurosurg, Athens 11561, Greece

[2] Childrens Hosp Agia Sofia, Dept Pathol, Athens 11561, Greece

[3] Univ Athens, Childrens Hosp Agia Sofia, Dept Pediat 1, Dept Hematol Oncol, Athens, Greece

来源：

NEUROPEDIATRICS | 2012年 / 43卷 / 03期

关键词：

medulloblastoma; fragile X syndrome; children; ACTIVATION; EXPRESSION; PATHWAY; TUMORS; RISK; ERK;

D O I：

10.1055/s-0032-1315430

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Fragile X syndrome is the most common cause of inherited intellectual impairment and has been associated with decreased incidence of cancer. We present the case of an 11-year-old boy with a diagnosis of fragile X syndrome who presented with gait imbalance, headache, and episodes of vomiting. Radiological investigation revealed the presence of a posterior fossa tumor. The patient was operated upon and the tumor proved to be a medulloblastoma (MB). To the best of our knowledge this is the first reported case of MB in a child with fragile X syndrome.

引用

页码：155 / 158

页数：4

共 50 条

[41] FRAGILE X-SYNDROME
TURNER, G
[J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1991, 49 (04) : 35 - 35
[42] NEUROANATOMY OF THE FRAGILE X SYNDROME
REISS, A
FREUND, L
AYLWARD, E
[J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1991, 49 (04) : 159 - 159
[43] Fragile X syndrome and the amygdala
Chattarji, Sumantra
Suvrathan, Aparna
Kedia, Sonal
[J]. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 2012, 30 (08) : 638 - 638
[44] THE FRAGILE-X SYNDROME
HO, HZ
GLAHN, TJ
HO, JC
[J]. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 1988, 30 (02): : 257 - 261
[45] Astrocytes in fragile X syndrome
Talvio, Karo
Castren, Maija L.
[J]. FRONTIERS IN CELLULAR NEUROSCIENCE, 2024, 17
[46] FRAGILE-X SYNDROME
LYNCH, SA
[J]. IRISH MEDICAL JOURNAL, 1993, 86 (05) : 172 - 172
[47] THE FRAGILE X-SYNDROME
DELGIUDICE, E
POGGI, V
SARTORIO, R
CARROZZO, R
ROMANO, A
SIRONE, P
FIORE, M
[J]. RIVISTA ITALIANA DI PEDIATRIA-ITALIAN JOURNAL OF PEDIATRICS, 1986, 12 (04): : 442 - 444
[48] FRAGILE-X SYNDROME
WIEBE, E
WIEBE, A
[J]. CANADIAN FAMILY PHYSICIAN, 1994, 40 : 290 - 295
[49] Psychomotricity and fragile X syndrome
Safont-Tria, NB
[J]. REVISTA DE NEUROLOGIA, 2001, 33 : S77 - S81
[50] HYPERACTIVITY AND THE FRAGILE X SYNDROME
EINFELD, S
HALL, W
LEVY, F
[J]. JOURNAL OF ABNORMAL CHILD PSYCHOLOGY, 1991, 19 (03) : 253 - 262

← 1 2 3 4 5 →