Labeling of FPEB with carbon-11 for evaluation as an mGluR5 radioligand in monkey with PET

被引:0
|
作者
Simeon, Fabrice G. [1 ]
Yi Zhang [1 ]
Morse, Cheryl L. [1 ]
Yoo, Chul H. [1 ]
Gladding, Robert L. [1 ]
Fujita, Masahiro [1 ]
Innis, Robert B. [1 ]
Pike, Victor W. [1 ]
机构
[1] NIMH, Mol Imaging Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
暂无
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
P242
引用
收藏
页码:S329 / S329
页数:1
相关论文
共 50 条
  • [41] In vitro characterization of [3H]MethoxyPyEP, an mGluR5 selective radioligand
    Patel, S
    Krause, SM
    Hamill, T
    Chaudhary, A
    Burns, DH
    Gibson, RA
    LIFE SCIENCES, 2003, 73 (03) : 371 - 379
  • [42] Direct labeling of peptides with carbon-11 for the synthesis of radiopharmaceuticals for positron emission tomography (PET)
    Chin, Joshua
    Vesnaver, Matthew
    Bernard-Gauthier, Vadim
    Lennox, R. Bruce
    Schirrmacher, Ralf
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2013, 56 : S95 - S95
  • [43] Carbon-11 labelling of MADAM in two different positions: a highly selective PET radioligand for the serotonin transporter
    Tarkiainen, J
    Vercouille, J
    Emond, P
    Sandell, J
    Hiltunen, J
    Frangin, Y
    Guilloteau, D
    Halldin, C
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2001, 44 (14): : 1013 - 1023
  • [44] Bolus vs. bolus/infusion of the mGluR5 tracer [18F]FPEB in humans
    Sullivan, Jenna
    Lim, Keunpoong
    Labaree, David
    Lin, Shu-fei
    McCarthy, Timothy
    Seibyl, John
    Tamagnan, Gilles
    Carson, Richard
    Ding, Yu-Shin
    Morris, Evan
    JOURNAL OF NUCLEAR MEDICINE, 2011, 52
  • [45] PET imaging of metabotropic glutamate receptor subtype 5 (mGluR5)
    Li, Dan
    Shan, Hong
    Conti, Peter
    Li, Zibo
    AMERICAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 2 (01): : 29 - 32
  • [46] Optimized synthesis of [18F]FPEB and preliminary neuroimaging of mGlur5 in transgenic mouse models
    Varlow, Cassis
    Stephenson, Nickeisha
    Murrell, Emily
    Vasdev, Neil
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2021, 41 (1_SUPPL): : 27 - 28
  • [47] Microdose PET for the metabotropic glutamate receptor type 5 (mGluR5)
    Brasic, James
    Mishra, Chakradhar
    Mathur, Anil
    Sweeney, Kristie
    Folsom, Timothy
    Kitzmiller, Kelly
    Mellinger-Pilgrim, Rebecca
    Wong, Dean
    Fatemi, S.
    JOURNAL OF NUCLEAR MEDICINE, 2018, 59
  • [48] Preclinical Evaluation and Quantification of 18F-FPEB as a Radioligand for PET Imaging of the Metabotropic Glutamate Receptor 5
    de Laat, Bart
    Leurquin-Sterk, Gil
    Celen, Sofie
    Bormans, Guy
    Koole, Michel
    Van Laere, Koen
    Casteels, Cindy
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (12) : 1954 - 1959
  • [49] Automated radiosynthesis of mGluR5 PET tracer [18F]FPEB from aryl-chloro precursor and validation for clinical application
    Jahan, Mahabuba
    Amir, Arsalan
    Das, Arindam
    Kihlstroem, Jacob
    Nag, Sangram
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2024, 67 (04): : 155 - 164
  • [50] Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey substantia nigra
    Hubert, GW
    Paquet, M
    Smith, Y
    JOURNAL OF NEUROSCIENCE, 2001, 21 (06): : 1838 - 1847