The effect of continuous intrathecal baclofen therapy on ambulatory children with cerebral palsy

被引：7

作者：

Pruszczynski, Blazej ^{[1
]}

Sees, Julieanne ^{[2
]}

Hulbert, Robert ^{[3
]}

Church, Chris ^{[3
]}

Henley, John ^{[3
]}

Niiler, Tim ^{[3
]}

Miller, Freeman ^{[2
]}

机构：

[1] Med Univ Lodz, Clin Orthopaed & Paediat Orthopaed, Lodz, Poland

[2] Nemours Alfred I duPont Hosp Children, Dept Orthoped, POB 269, Wilmington, DE 19899 USA

[3] Nemours Alfred I duPont Hosp Children, Gait Lab, Wilmington, DE USA

来源：

JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B | 2018年 / 27卷 / 03期

关键词：

baclofen pump; cerebral palsy; gait analysis; spasticity; tone management; T-TEST; RELIABILITY; SPASTICITY; ADOLESCENTS; NORMALITY; DYSTONIA; EFFICACY; INFUSION;

D O I：

10.1097/BPB.0000000000000462

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The effect of a continuous intrathecal infusion of baclofen (CITB) was retrospectively studied in 19 ambulatory children with cerebral palsy (aged 12.4 +/- 4.9 years at CITB initiation). The mean clinical follow-up was 5.1 +/- 2.4 years and the mean follow-up gait analysis was 2.8 +/- 1.9 years. Spastic cerebral palsy diagnosis [14 (74%)] was most frequent. Most patients [11 (58%)] were Gross Motor Function Classification System level III. CITB significantly improved muscle tone and knee flexion at initial contact (P<0.05), but it did not lead to improved gait speed or gross motor function.

引用

页码：214 / 220

页数：7

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