Molecular Imaging Biomarkers for Oncology Clinical Trials

被引：55
|
作者：
Mankoff, David A. [1 ]
Pryma, Daniel A. [1 ]
Clark, Amy S. [2 ]
机构：
[1] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Philadelphia, PA 19104 USA
来源：
JOURNAL OF NUCLEAR MEDICINE | 2014年 / 55卷 / 04期
关键词：
cancer biomarkers; clinical trials; cancer therapy; BREAST-CANCER; FDG-PET; TRASTUZUMAB; CRITERIA;
D O I：
10.2967/jnumed.113.126128
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Biomarkers can be used to characterize disease status or predict disease behavior. Cancer biomarkers have typically relied on assays of blood or tissue; however, molecular imaging has a promising and complementary role as a cancer biomarker. This "Focus on Molecular Imaging" article reviews the current role of biomarkers to direct cancer clinical trials and clinical practice, along with current and future cancer biomarker applications of molecular imaging.
引用
收藏
页码：525 / 528
页数：4
相关论文
共 50 条
  • [41] Innovative molecular imaging approaches for radiation oncology: new PET biomarkers and "Radiomics"
    Lambin, P.
    Dubois, L.
    Aerts, H.
    Eriksson, J.
    Windhorst, B.
    De Ruysscher, D.
    van Dongen, G.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2011, 187 (09) : 594 - 594
  • [42] Imaging Biomarkers in Atherosclerosis Trials
    Tardif, Jean-Claude
    Lesage, Frederic
    Harel, Francois
    Romeo, Philippe
    Pressacco, Josephine
    CIRCULATION-CARDIOVASCULAR IMAGING, 2011, 4 (03) : 319 - 333
  • [43] Evolving Landscape of Molecular Prescreening Strategies for Oncology Early Clinical Trials
    Dienstmann, Rodrigo
    Garralda, Elena
    Aguilar, Susana
    Sala, Gemma
    Viaplana, Cristina
    Ruiz-Pace, Fiorella
    Gonzalez-Zorelle, Jenifer
    Grazia LoGiacco, Deborah
    Ogbah, Zighereda
    Ramos Masdeu, Laia
    Mancuso, Francesco
    Fasani, Roberta
    Jimenez, Jose
    Martinez, Paola
    Oaknin, Ana
    Saura, Cristina
    Oliveira, Mafalda
    Balmana, Judith
    Carles, Joan
    Macarulla, Teresa
    Elez, Elena
    Alsina, Maria
    Brana, Irene
    Felip, Enriqueta
    Tabernero, Josep
    Rodon, Jordi
    Nuciforo, Paolo
    Vivancos, Ana
    JCO PRECISION ONCOLOGY, 2020, 4 : 505 - 513
  • [44] A GLOBAL, MOLECULAR DISEASE CHARACTERIZATION INITIATIVE (MDCI) IN ONCOLOGY CLINICAL TRIALS
    Johnson, Melissa
    Sacher, Adrian
    Butler, Marcus
    Zarour, Hassane
    Weber, Jeffrey
    Garon, Edward
    Carbone, David
    Dhar, Arindam
    Messina, Cristina
    Patel, Roma
    Blouch, Kristin
    Hoos, Axel
    Martin, Anne-Marie
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 : A423 - A423
  • [45] Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era
    Azria, David
    Lapierre, Ariane
    Gourgou, Sophie
    De Ruysscher, Dirk
    Colinge, Jacques
    Lambin, Philippe
    Brengues, Muriel
    Ward, Tim
    Bentzen, Soren M.
    Thierens, Hubert
    Rancati, Tiziana
    Talbot, Christopher J.
    Vega, Ana
    Kerns, Sarah L.
    Andreassen, Christian Nicolaj
    Chang-Claude, Jenny
    West, Catharine M. L.
    Gill, Corey M.
    Rosenstein, Barry S.
    FRONTIERS IN ONCOLOGY, 2017, 7
  • [46] Clinical Trials in Molecular Imaging: The Importance of Following the Protocol
    Trembath, LisaAnn
    Opanowski, Adam
    JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY, 2011, 39 (02) : 63 - 69
  • [47] Molecular imaging as a cancer biomarker in clinical trials.
    Mankoff, D.
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (02) : 25 - 26
  • [48] Imaging Biomarkers in Lymphangioleiomyomatosis Clinical Trials A Wolf in Sheep's Clothing?
    Washko, George R.
    Parraga, Grace
    ANNALS OF THE AMERICAN THORACIC SOCIETY, 2016, 13 (03) : 307 - 308
  • [49] Endpoints in oncology clinical trials
    Kilickap, Saadettin
    Demirci, Umut
    Karadurmus, Nuri
    Dogan, Mutlu
    Akinci, Bulent
    Sendur, Mehmet Ali Nahit
    JOURNAL OF BUON, 2018, 23 : S1 - S6
  • [50] Molecular imaging in oncology
    Sullivan, D. C.
    ANNALS OF ONCOLOGY, 2006, 17 : X287 - X292
12345