Myxobacterial epothilones and tubulysins as promising anticancer agents

被引：36

作者：

Doemling, Alexander ^{[1
]}

Richter, Wolfgang ^{[1
]}

机构：

[1] R&D Biopharmaceut, Munich, Germany

来源：

MOLECULAR DIVERSITY | 2005年 / 9卷 / 1-3期

关键词：

epothilone; tubulin binder; tubulysin;

D O I：

10.1007/s11030-005-1542-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tubulin-binding agents play a pivotal role in current cancer therapy and there are many efforts in pre-clinical and clinical development of known and novel cytotoxic agents ongoing. In this article a known class, epothilones, as well as a novel class, tubulysins, are presented.

引用

页码：141 / 147

页数：7

共 50 条

[1] Myxobacterial epothilones and tubulysins as promising anticancer agents
Alexander Dömling
Wolfgang Richter
[J]. Molecular Diversity, 2005, 9 : 141 - 147
[2] Epothilones A and B: Springboards for semisynthesis of promising antimitotic agents.
Vite, G
Borzilleri, R
Fooks, C
Johnson, J
Kim, SH
Leavitt, K
Mitt, T
Regueiro-Ren, A
Schmidt, R
Zheng, P
Lee, F
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U138 - U138
[3] Flavonoids: Promising anticancer agents
Ren, WY
Qiao, ZH
Wang, HW
Zhu, L
Zhang, L
[J]. MEDICINAL RESEARCH REVIEWS, 2003, 23 (04) : 519 - 534
[4] Sirtuin inhibitors as promising anticancer agents
Lin, Hening
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
[5] The development of chalcones as promising anticancer agents
Ducki, Sylvie
[J]. IDRUGS, 2007, 10 (01) : 42 - 46
[6] Coumarin: A Promising Scaffold for Anticancer Agents
Kaur, Manjinder
Kohli, Swarandeep
Sandhu, Sonali
Bansal, Yogita
Bansal, Gulshan
[J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2015, 15 (08) : 1032 - 1048
[7] Spirooxindoles: Promising scaffolds for anticancer agents
Yu, Bin
Yu, De-Quan
Liu, Hong-Min
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 97 : 673 - 698
[8] Tetrazole Derivatives as Promising Anticancer Agents
Popova, Elena A.
Protas, Aleksandra V.
Trifonov, Rostislav E.
[J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2017, 17 (14) : 1856 - 1868
[9] Signal Transduction Inhibitors as Promising Anticancer Agents
Kumar, Raj
Dos Santos, Cedric
Ahluwalia, Tarunveer Singh
Singh, Sandeep
[J]. BIOMED RESEARCH INTERNATIONAL, 2015, 2015
[10] Discovery of Isoerianin Analogues as Promising Anticancer Agents
Messaoudi, Samir
Hamze, Abdallah
Provot, Olivier
Treguier, Bret
De Losada, Jordi Rodrigo
Bignon, Jerome
Liu, Jian-Miao
Wdzieczak-Bakala, Joanna
Thoret, Sylviane
Dubois, Joelle
Brion, Jean-Daniel
Alami, Mouad
[J]. CHEMMEDCHEM, 2011, 6 (03) : 488 - 497

← 1 2 3 4 5 →