Human histone H3K79 methyltransferase DOT1L protein binds actively transcribing RNA polymerase II to regulate gene expression (vol 287, pg 39698, 2012)

被引:0
|
作者
Kim, Seung-Kyoon
Jung, Inkyung
Lee, Hosuk
Kang, Keunsoo
Kim, Mirang
Jeong, Kwiwan
Kwon, Chang Seob
Han, Yong-Mahn
Kim, Yong Sung
Kim, Dongsup
Lee, Daeyoup
机构
关键词
D O I
10.1074/jbc.A112.384057
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:295 / 295
页数:1
相关论文
共 35 条
  • [21] Myeloid Leukemia Cells With MLL partial Tandem Duplication Are Sensitive To Pharmacological Inhibition Of The H3K79 Methyltransferase DOT1L
    Kuhn, Michael W. M.
    Hadler, Michael
    Daigle, Scott R.
    Chen, Chun-Wei
    Sinha, Amit U.
    Krivtsov, Andrei V.
    Olhava, Edward J.
    Caligiuri, Michael A.
    Bradner, James E.
    Pollock, Roy M.
    Armstrong, Scott A.
    BLOOD, 2013, 122 (21)
  • [22] Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer
    Yang, Liqun
    Lei, Qian
    Li, Lin
    Yang, Jie
    Dong, Zhen
    Cui, Hongjuan
    CLINICAL EPIGENETICS, 2019, 11 (01)
  • [23] Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer
    Liqun Yang
    Qian Lei
    Lin Li
    Jie Yang
    Zhen Dong
    Hongjuan Cui
    Clinical Epigenetics, 2019, 11
  • [24] Hesperetin promotes DOT1L degradation and reduces histone H3K79 methylation to inhibit gastric cancer metastasis (vol 84,153499,2021)
    Wang, Si-Wei
    Sheng, Hao
    Zheng, Fang
    Zhang, Feng
    PHYTOMEDICINE, 2025, 136
  • [25] Neuronal Dot1l Activity Acts as a Mitochondrial Gene-Repressor Associated with Human Brain Aging via H3K79 Hypermethylation
    Van Heesbeen, Hendrikus J.
    Von Oerthel, Lars
    De Vries, Paul M.
    Wagemans, Cindy M. R. J.
    Smidt, Marten P.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (02)
  • [26] DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells
    Steger, David J.
    Lefterova, Martina I.
    Ying, Lei
    Stonestrom, Aaron J.
    Schupp, Michael
    Zhuo, David
    Vakoc, Adam L.
    Kim, Ja-Eun
    Chen, Junjie
    Lazar, Mitchell A.
    Blobel, Gerd A.
    Vakoc, Christopher R.
    MOLECULAR AND CELLULAR BIOLOGY, 2008, 28 (08) : 2825 - 2839
  • [27] Depletion of H3K79 methyltransferase Dot1L promotes cell invasion and cancer stem-like cell property in ovarian cancer
    Wang, Xian
    Wang, Hua
    Xu, Bo
    Jiang, Dongrui
    Huang, Shan
    Yu, Hongzhen
    Wu, Zhengsheng
    Wu, Qiang
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2019, 11 (02): : 1145 - 1153
  • [28] Correction to: Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer
    Liqun Yang
    Qian Lei
    Lin Li
    Jie Yang
    Zhen Dong
    Hongjuan Cui
    Clinical Epigenetics, 2022, 14
  • [29] Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer (vol 11, 199, 2019)
    Yang, Liqun
    Lei, Qian
    Li, Lin
    Yang, Jie
    Dong, Zhen
    Cui, Hongjuan
    CLINICAL EPIGENETICS, 2022, 14 (01)
  • [30] Loss of Histone H3 K79 Methyltransferase Dot1l Facilitates Kidney Fibrosis by Upregulating Endothelin 1 through Histone Deacetylase 2
    Zhang, Long
    Chen, Lihe
    Gao, Chao
    Chen, Enuo
    Lightle, Andrea R.
    Foulke, Llewellyn
    Zhao, Bihong
    Higgins, Paul J.
    Zhang, Wenzheng
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2020, 31 (02): : 337 - 349