Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

被引:7
|
作者
Mackin, Kate E. [1 ]
Elliott, Briony [2 ]
Kotsanas, Despina [3 ]
Howden, Benjamin P. [4 ,5 ]
Carter, Glen P. [1 ]
Korman, Tony M. [3 ,6 ]
Riley, Thomas V. [2 ,7 ]
Rood, Julian I. [1 ]
Jenkin, Grant A. [3 ]
Lyras, Dena [1 ]
机构
[1] Monash Univ, Dept Microbiol, Clayton, Vic 3800, Australia
[2] Univ Western Australia, Sch Pathol & Lab Med, Nedlands, WA 6009, Australia
[3] Monash Hlth, Monash Infect Dis, Clayton, Vic, Australia
[4] Austin Hlth, Dept Microbiol, Heidelberg, Vic, Australia
[5] Univ Melbourne, Dept Microbiol & Immunol, Melbourne, Vic 3010, Australia
[6] Monash Hlth, Dept Microbiol, Clayton, Vic, Australia
[7] PathWest Lab Med, Nedlands, WA, Australia
基金
澳大利亚国家健康与医学研究理事会; 澳大利亚研究理事会; 英国医学研究理事会;
关键词
Clostridium difficile; Clostridium difficile epidemiology; Clostridium difficile toxinotypes; Clostridium difficile Australia; Clostridium difficile antibiotic resistance; FUSIDIC ACID; PATHOGENICITY LOCUS; RESISTANCE; INFECTION; RIBOTYPE; VANCOMYCIN; EMERGENCE; TOXIN; METRONIDAZOLE; EPIDEMIOLOGY;
D O I
10.1016/j.anaerobe.2015.05.001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:80 / 83
页数:4
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