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Shandong First Med Univ & Shandong Acad Med Sci, State Key Lab Cultivat Base, Shandong Prov Key Lab Ophthalmol, Shandong Eye Inst, Qingdao, Shandong, Peoples R China Shandong First Med Univ & Shandong Acad Med Sci, State Key Lab Cultivat Base, Shandong Prov Key Lab Ophthalmol, Shandong Eye Inst, Qingdao, Shandong, Peoples R China