We consider the variant of the Two-Dimensional Bin Packing Problem in which items have to be obtained by a series of guillotine cuts and cannot be rotated. We present a heuristic algorithm based on partial enumeration, and computationally evaluate its performance on a large set of instances from the literature. Computational experiments show that the algorithm is able to produce proven optimal solutions for a large number of problems, and gives a tight approximation of the optimum in the remaining cases. (C) 2015 Elsevier B.V. All rights reserved.