PRODUCTION OF OLEANOLIC AND URSOLIC ACIDS BY CALLUS CULTURES OF SALVIA TOMENTOSA MILL.

被引：10

作者：

Georgiev, Vasil ^{[1
]}

Marchev, Andrey ^{[1
]}

Haas, Christiane ^{[2
]}

Weber, Jost ^{[2
]}

Nikolova, Milena ^{[3
]}

Bley, Thomas ^{[2
]}

Pavlov, Atanas ^{[1
,4
]}

机构：

[1] Bulgarian Acad Sci, Stephan Angeloff Inst Microbiol, Lab Appl Biotechnol, Plovdiv, Bulgaria

[2] Tech Univ Dresden, Inst Food Technol & Bioproc Engn, D-01062 Dresden, Germany

[3] Bulgarian Acad Sci, Inst Biodivers & Ecosyst Res, Sofia, Bulgaria

[4] Univ Food Technol, Dept Organ Chem & Microbiol, Plovdiv, Bulgaria

来源：

BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT | 2011年 / 25卷

关键词：

sage; triterpenic acids; in vitro systems; somaclonal variation; polyploidy; flow cytometry;

D O I：

10.5504/bbeq.2011.0129

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Callus cultures of Salvia tomentosa Mill. were induced and analyzed for their capacity to produce oleanolic and ursolic acids. The obtained callus lines showed high variability in their biosynthetic potentials. Flow cytometric investigations showed that this variability was due to polyploidization of plant cells in calli. Polyploidization of callus cell seems to be promoted by the growth regulators used for callus induction. One octaploid line (consisting of 8C, 16C and 32C cells) was selected as prospective producer of oleanolic (991.57 mu g/g DW) and ursolic (641.85 mu g/g DW) acids. To our knowledge, this is the first report for obtaining of triterpenes producing callus culture of S. tomentosa Mill.

引用

页码：34 / 38

页数：5

共 39 条

[1] Salvia suspension cultures as production systems for oleanolic and ursolic acid
Haas, Christiane
Hengelhaupt, Karl-Christoph
Kuemmritz, Sibylle
Bley, Thomas
Pavlov, Atanas
Steingroewer, Juliane
ACTA PHYSIOLOGIAE PLANTARUM, 2014, 36 (08) : 2137 - 2147
[2] Salvia suspension cultures as production systems for oleanolic and ursolic acid
Christiane Haas
Karl-Christoph Hengelhaupt
Sibylle Kümmritz
Thomas Bley
Atanas Pavlov
Juliane Steingroewer
Acta Physiologiae Plantarum, 2014, 36 : 2137 - 2147
[3] Essential-Oil Diversity of Salvia tomentosa Mill. in Greece
Hanlidou, Effie
Karousou, Regina
Lazari, Diamanto
CHEMISTRY & BIODIVERSITY, 2014, 11 (08) : 1205 - 1215
[4] The determination of total phenolics and flavonoid contents, and antioxidant activity of some sage populations of Salvia fruticosa Mill., Salvia pomifera Mill. and Salvia tomentosa Mill. in the Marmara region of Turkey
Erdogan, S. S.
Karik, U.
Baser, K. H. C.
PLANTA MEDICA, 2011, 77 (12) : 1319 - 1319
[5] Induced accumulation of oleanolic acid and ursolic acid in cell suspension cultures of Uncaria tomentosa
Feria-Romero, I
Lazo, E
Ponce-Noyola, T
Cerda-García-Rojas, CM
Ramos-Valdivia, AC
BIOTECHNOLOGY LETTERS, 2005, 27 (12) : 839 - 843
[6] Induced accumulation of oleanolic acid and ursolic acid in cell suspension cultures of Uncaria tomentosa
Iris Feria-Romero
Elizabeth Lazo
Teresa Ponce-Noyola
Carlos M. Cerda-García-Rojas
Ana C. Ramos-Valdivia
Biotechnology Letters, 2005, 27 : 839 - 843
[7] Preparation and Evaluation of a Novel Organogel Formulation of Salvia tomentosa Mill. Essential Oil
Haznedaroglu, Mehmet Z.
Yurdasiper, Aysu
Koyu, Halil
Yalcin, Gorkem
Ozturk, Ismail
Gokce, Evren H.
LATIN AMERICAN JOURNAL OF PHARMACY, 2013, 32 (06): : 845 - 851
[8] Chemical Specification of Wild Salvia tomentosa Mill. Collected From Inner Aegean Region of Turkey
Soltanbeigi, Amir
Sakartepe, Erhan
ZEITSCHRIFT FUR ARZNEI- & GEWURZPFLANZEN, 2020, 25 (01): : 31 - 35
[9] Features of Growth and Accumulation of Polyphenolic Compounds in Callus Cultures of Lavandula angustifolia Mill.
Ivanov, P. A.
Khabarov, V. A.
Nekrasova, D. A.
Pivovarova, N. S.
Whaley, A. K.
Povydysh, M. N.
RUSSIAN JOURNAL OF PLANT PHYSIOLOGY, 2024, 71 (03)
[10] Two-phase temporary immersion system for Agrobacterium rhizogenes genetic transformation of sage (Salvia tomentosa Mill.)
Marchev, Andrey
Georgiev, Vasil
Ivanov, Ivan
Badjakov, Ilian
Pavlov, Atanas
BIOTECHNOLOGY LETTERS, 2011, 33 (09) : 1873 - 1878

← 1 2 3 4 →