Induced accumulation of oleanolic acid and ursolic acid in cell suspension cultures of Uncaria tomentosa

被引：21
|
作者：
Feria-Romero, I
Lazo, E
Ponce-Noyola, T
Cerda-García-Rojas, CM
Ramos-Valdivia, AC
机构：
[1] Inst Politecn Nacl, Ctr Invest & Estudios Avanzados, Dept Biotecnol & Bioingn, Mexico City 07360, DF, Mexico
[2] Inst Politecn Nacl, Ctr Invest & Estudios Avanzados, Dept Quim, Mexico City 07360, DF, Mexico
来源：
BIOTECHNOLOGY LETTERS | 2005年 / 27卷 / 12期
关键词：
cell cultures; jasmonic acid; sucrose supply; Uncaria tomentosa; ursolic and oleanolic acids;
D O I：
10.1007/s10529-005-6215-7
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Increasing sucrose from 20 to 50 g l(-1) in Uncaria tomentosa cell suspension cultures enhanced ursolic acid and oleanolic acid production from 129 +/- 61 to 553 +/- 193 mu g g(-1) cell dry wt. The maximal concentration of both triterpenes (1680 +/- 39 mu g g(-1) cell dry wt) was 8 days after elicitation by jasmonic acid, while yeast extract or citrus pectin treatments produced 1189 +/- 20 or 1120 +/- 26 mu g g(-1) cell dry wt, respectively. The ratio of ursolic acid:oleanolic acid was constant at 70:30.
引用
收藏
页码：839 / 843
页数：5
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