Overcoming cisplatin resistance in chemotherapy by biomineralization

被引:26
|
作者
Chen, Wei [1 ]
Xiao, Yun [1 ]
Liu, Xueyao [1 ]
Chen, Yanhong [2 ]
Zhang, Jiaojiao [1 ]
Xu, Xurong [3 ]
Tang, Ruikang [1 ,3 ]
机构
[1] Zhejiang Univ, Dept Chem, Ctr Biomat & Biopathways, Hangzhou 310027, Zhejiang, Peoples R China
[2] Zhejiang Univ, Lab Anim Ctr, Hangzhou 310058, Zhejiang, Peoples R China
[3] Zhejiang Univ, Qiushi Acad Adv Studies, Hangzhou 310027, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
NANOPARTICLE; MECHANISMS;
D O I
10.1039/c3cc41872c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nano-solidified intermedias (NSI) of cisplatin were prepared via biomineralization and applied to reverse the drug resistance of cancers in vitro and in vivo by an alternative internalization pathway.
引用
收藏
页码:4932 / 4934
页数:3
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