Deep Learning Models Explore the Structural Effects of Transcription Factor-DNA Complexes on Binding Specificity

被引：0
|
作者：
Shimko, Tyler C. [1 ]
Fordyce, Polly M. [1 ]
机构：
[1] Stanford Univ, Genet, Stanford, CA 94305 USA
来源：
BIOPHYSICAL JOURNAL | 2019年 / 116卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2018.11.2714
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
2494-Pos
引用
收藏
页码：503A / 503A
页数：1
相关论文
共 50 条
  • [1] Stability selection for regression-based models of transcription factor-DNA binding specificity
    Mordelet, Fantine
    Horton, John
    Hartemink, Alexander J.
    Engelhardt, Barbara E.
    Gordan, Raluca
    BIOINFORMATICS, 2013, 29 (13) : 117 - 125
  • [2] Eukaryotic transcription factor-DNA complexes
    Patikoglou, G
    Burley, SK
    ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 1997, 26 : 289 - 325
  • [3] Biophysical and structural characterization of transcription factor-DNA binding in Drosophila melanogaster
    Mekkaoui, Fadwa
    Advocate, Mia R.
    Dresch, Jacqueline M.
    Drewell, Robert A.
    Spratt, Donald E.
    PROTEIN SCIENCE, 2023, 32 (12)
  • [4] Analysis of DNA deformations in transcription factor-DNA complexes
    Sagendorf, Jared
    Berman, Helen M.
    Rohs, Remo
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2015, 33 : 16 - 16
  • [5] Measuring quantitative effects of methylation on transcription factor-DNA binding affinity
    Zuo, Zheng
    Roy, Basab
    Chang, Yiming Kenny
    Granas, David
    Stormo, Gary D.
    SCIENCE ADVANCES, 2017, 3 (11):
  • [6] Mechanisms of organoselenium compounds in chemoprevention: Effects on transcription factor-DNA binding
    Youn, BW
    Fiala, ES
    Sohn, OS
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2001, 40 (01): : 28 - 33
  • [7] Transcription factor-DNA binding: beyond binding site motifs
    Inukai, Sachi
    Kock, Kian Hong
    Bulyk, Martha L.
    CURRENT OPINION IN GENETICS & DEVELOPMENT, 2017, 43 : 110 - 119
  • [8] pH dynamics regulates transcription factor-DNA binding
    Kisor, Kyle
    Barber, Diane
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 214A - 215A
  • [9] Quantifying Intensities of Transcription Factor-DNA Binding by Learning From an Ensemble of Protein Binding Microarrays
    Quan, Lijun
    Mei, Jie
    He, Ruji
    Sun, Xiaoyu
    Nie, Liangpeng
    Li, Kailong
    Lyu, Qiang
    IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 2021, 25 (07) : 2811 - 2819
  • [10] BIOPHYSICAL AND STRUCTURAL ANALYSIS OF ANTENNAPEDIA AND ULTRABITHORAX HOMEODOMAIN TRANSCRIPTION FACTOR-DNA BINDING AFFINITIES
    Loss, Jeanmarie W.
    Orlomoski, Rachel J.
    Dresch, Jacqueline M.
    Drewell, Robert A.
    Spratt, Donald E.
    PROTEIN SCIENCE, 2019, 28 : 142 - 142
12345