Molecular pathological identification of predictive biomarkers. A new task for diagnostic pathology

被引:0
|
作者
Schmid, K. W. [1 ]
机构
[1] Univ Duisburg Essen, Univ Klinikum Essen, Inst Pathol & Neuropathol, D-45134 Essen, Germany
来源
UROLOGE | 2008年 / 47卷 / 10期
关键词
Predictive biomarkers; Molecular pathological identification; Cancer patients;
D O I
10.1007/s00120-008-1745-y
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The clinical management of cancer patients is still based to a great extent on the histological staging, grading, and tumor typing performed by the pathologist. As a result part of the patients are subjected to unnecessary treatment regimens with high rates of side effects and no advantages while another part of the patients could benefit from (adjuvant) therapies they would not routinely receive based on their tumor staging/grading. This situation has led to a search for so-called predictive biomarkers, which would allow better assessment of the clinical course, probability of metastases, and the efficacy of the treatment method, thus making it possible to individualize treatment for each cancer patient.
引用
收藏
页码:1298 / +
页数:4
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