Role of developmental overnutrition in pediatric obesity and type 2 diabetes

被引：39

作者：

Dabelea, Dana ^{[1
]}

Harrod, Curtis S. ^{[1
]}

机构：

[1] Univ Colorado Denver, Colorado Sch Publ Hlth, Dept Epidemiol, Aurora, CO 80045 USA

来源：

NUTRITION REVIEWS | 2013年 / 71卷

关键词：

childhood obesity; developmental overnutrition; pediatrics; type; 2; diabetes; BODY-MASS INDEX; GESTATIONAL WEIGHT-GAIN; BIRTH-WEIGHT; OFFSPRING OBESITY; FAT DISTRIBUTION; INCREASING PREVALENCE; INTRAUTERINE EXPOSURE; CHILDHOOD OBESITY; MATERNAL OBESITY; IN-UTERO;

D O I：

10.1111/nure.12061

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Childhood obesity continues to be a significant public health burden. Empirical evidence has begun to identify intrauterine and postnatal pathways that increase the likelihood of excess adiposity and increased risk of type 2 diabetes among offspring. Reviewed here is the evidence supporting a transgenerational vicious cycle that increases obesity and diabetes in offspring and contributes substantially to the increases in obesity and type 2 diabetes observed over the past several decades. The public health impact of these findings is discussed and future research opportunities are outlined. (C) 2013 International Life Sciences Institute

引用

页码：S62 / S67

页数：6

共 50 条

[41] Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes
Zorzano, Antonio
Liesa, Marc
Palacin, Manuel
[J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2009, 41 (10): : 1846 - 1854
[42] Role of obesity and lifestyle interventions in the prevention and management of type 2 diabetes
Davis, N.
Forbes, B.
Wylie-Rosett, J.
[J]. MINERVA MEDICA, 2009, 100 (03) : 221 - 228
[43] Prevalence and role of obesity and hypertension in type 2 diabetes mellitus patients
Disoteo, O.
Pizzi, G.
Fossati, C.
[J]. JOURNAL OF HYPERTENSION, 2007, 25 : S192 - S192
[44] The role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity
Tai, Ningwen
Wong, F. Susan
Wen, Li
[J]. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2015, 16 (01): : 55 - 65
[45] The role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity
Ningwen Tai
F. Susan Wong
Li Wen
[J]. Reviews in Endocrine and Metabolic Disorders, 2015, 16 : 55 - 65
[46] Developmental Origins of Pediatric Obesity
Gahagan, Sheila
Uauy, Ricardo
Roseboom, Tessa J.
[J]. INTERNATIONAL JOURNAL OF PEDIATRICS, 2012, 2012
[47] Developmental origins of Type 2 diabetes
Ozanne, Susan
[J]. DIABETES RESEARCH AND CLINICAL PRACTICE, 2008, 79 : S2 - S3
[48] Decreased Quality of Life in Pediatric Patients with Obesity and at Risk for Type 2 Diabetes Mellitus
Zhao, Alice
Lin-Su, Karen
D'Angelo, Debra
Censani, Marisa
[J]. HORMONE RESEARCH IN PAEDIATRICS, 2020, 93 : 8 - 8
[49] Pediatric obesity in a native Canadian community with epidemic levels of type 2 diabetes mellitus
Hanley, A
Harris, S
Gittelsohn, H
Wolever, T
Saksvig, B
Zinman, B
[J]. DIABETES, 1999, 48 : A169 - A169
[50] Developmental Origins of β-Cell Failure in Type 2 Diabetes: The Role of Epigenetic Mechanisms
Rebecca A Simmons
[J]. Pediatric Research, 2007, 61 : 64 - 67

← 1 2 3 4 5 →