Improving Risk Assessment

被引：11

作者：

Dambach, Donna M. ^{[1
]}

Uppal, Hirdesh ^{[1
]}

机构：

[1] Genentech Inc, Safety Assessment Dev Sci, San Francisco, CA 94080 USA

来源：

SCIENCE TRANSLATIONAL MEDICINE | 2012年 / 4卷 / 159期

关键词：

INDUCED LIVER-INJURY; HEPATIC-METABOLISM; ORAL MEDICATIONS; DRUG; TOXICOLOGY; TOXICITY; LESSONS; DESIGN; CHIP;

D O I：

10.1126/scitranslmed.3003497

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Widespread sharing and analysis of clinical trial data and a U.S. government initiative to engineer nonclinical cell-based models that mimic human biological processes have the potential to improve predictions of drug-related adverse events.

引用

页数：5

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