A phase 3 trial comparing ixekizumab with placebo and etanercept for moderate-to-severe plaque psoriasis: Results from the 12 week induction period of UNCOVER 3

被引:0
|
作者
Griffiths, Christopher E. [1 ]
Reich, Kristian [2 ]
Lebwohl, Mark [3 ]
Van de Kerkhof, Peter [4 ]
Paul, Carle [5 ]
Menter, Alan [6 ]
Carlier, Hilde [7 ]
Cameron, Gregory [7 ]
Erickson, Janelle [7 ]
Zhang, Lu [7 ]
Secrest, Roberta [7 ]
Ball, Susan [7 ]
Braun, Daniel [7 ]
Osuntokun, Olawale [7 ]
Heffernan, Michael [7 ]
Nickoloff, Brian [7 ]
Papp, Kim [8 ]
机构
[1] Univ Manchester, Inst Inflammat & Repair, Manchester, Lancs, England
[2] Dermatologickum Hamburg, Hamburg, Germany
[3] Icahn Sch Med Mt Sinai, Dept Dermatol, New York, NY 10029 USA
[4] Radboud Univ Nijmegen, Dept Dermatol, NL-6525 ED Nijmegen, Netherlands
[5] Univ Toulouse 3, Dept Dermatol, F-31062 Toulouse, France
[6] Univ Texas SW Med Ctr Dallas, SW Med Sch, Dallas, TX 75390 USA
[7] Eli Lilly & Co, Indianapolis, IN 46285 USA
[8] Prob Med Res, Waterloo, ON, Canada
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
P059
引用
收藏
页码:S17 / S17
页数:1
相关论文
共 50 条
  • [31] Efficacy of Ixekizumab in Patients with and without Previous Experience with Biologic Therapies Compared to Etanercept and Placebo: Results from UNCOVER-2, a Phase 3 Trial in Patients with Plaque Psoriasis
    Lacour, J. -P.
    Leutz, A.
    Dutronc, Y.
    Zhang, L.
    [J]. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2016, 14 : 4 - 4
  • [32] Impact of ixekizumab treatment on scalp psoriasis: results from the placebo-controlled induction period of UNCOVER-3
    Reich, K.
    Leonardi, C.
    Lebwohl, M.
    Romiti, R.
    Goldblum, O.
    Zhang, L.
    Shrom, D.
    Dennehy, E.
    Sofen, H.
    [J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2016, 30 : 73 - 73
  • [33] Efficacy of ixekizumab in patients with and without previous experience with biologic therapies compared to etanercept and placebo: results from UNCOVER-2, a phase 3 trial in patients with plaque psoriasis
    Lacour, Jean-Philippe
    Dutronc, Yves
    Zhang, Lu
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 : S6 - S6
  • [34] Efficacy and safety of ixekizumab treatment in Japanese patients with moderate-to-severe plaque psoriasis: Subgroup analysis of a placebo-controlled, phase 3 study (UNCOVER-1)
    Imafuku, Shinichi
    Torisu-Itakura, Hitoe
    Nishikawa, Atsushi
    Zhao, Fangyi
    Cameron, Gregory S.
    [J]. JOURNAL OF DERMATOLOGY, 2017, 44 (11): : 1285 - 1290
  • [35] Sustained response with ixekizumab treatment of moderate-to-severe psoriasis with scalp involvement: results from three phase 3 trials (UNCOVER-1, UNCOVER-2, UNCOVER-3)
    Reich, Kristian
    Leonardi, Craig
    Lebwohl, Mark
    Kerdel, Francisco
    Okubo, Yukari
    Romiti, Ricardo
    Goldblum, Orin
    Dennehy, Ellen B.
    Kerr, Lisa
    Sofen, Howard
    [J]. JOURNAL OF DERMATOLOGICAL TREATMENT, 2017, 28 (04) : 282 - 287
  • [36] Improvement in nail psoriasis in the open-label extension period of a phase 2 trial of ixekizumab in patients with moderate-to-severe plaque psoriasis
    Rich, P.
    Langley, R. G.
    Menter, A.
    Krueger, G. G.
    Zhu, B.
    Wei, H.
    Cameron, G. S.
    Heffernan, M. P.
    Holzkaemper, T.
    [J]. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2015, 13 : 135 - 136
  • [37] Efficacy and Safety of Switching to Ixekizumab in Etanercept Non-Responders: A Subanalysis from Two Phase III Randomized Clinical Trials in Moderate-to-Severe Plaque Psoriasis (UNCOVER-2 and -3)
    Andrew Blauvelt
    Kim A. Papp
    Christopher E. M. Griffiths
    Luis Puig
    Jamie Weisman
    Yves Dutronc
    Lisa Farmer Kerr
    Dapo Ilo
    Lotus Mallbris
    Matthias Augustin
    [J]. American Journal of Clinical Dermatology, 2017, 18 : 273 - 280
  • [38] Ixekizumab impact on the skin-related relationship problems of patients with moderate-to-severe plaque psoriasis: integrated results from three Phase 3 trials (UNCOVER-1,-2,-3)
    Warren, R. B.
    Cather, J.
    Ohtsuki, M.
    Bleakman, A. Potts
    Burge, R.
    Zhu, B.
    Reich, K.
    [J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2016, 30 : 77 - 78
  • [39] Effect of Ixekizumab Treatment on Work Productivity for Patients With Moderate-to-Severe Plaque Psoriasis Analysis of Results From 3 Randomized Phase 3 Clinical Trials
    Armstrong, April W.
    Lynde, Charles W.
    McBride, Sandy R.
    Stahle, Mona
    Edson-Heredia, Emily
    Zhu, Baojin
    Amato, David
    Nikai, Enkeleida
    Yang, Fan Emily
    Gordon, Kenneth B.
    [J]. JAMA DERMATOLOGY, 2016, 152 (06) : 661 - 669
  • [40] Ixekizumab for the treatment of moderate-to-severe plaque psoriasis: Sub-analysis of the Phase 3 UNCOVER trials in patients with baseline PASI > 15
    Spelman, L.
    Rubel, D.
    Brnabic, A.
    Burkhardt, N.
    Kelin, K.
    Gurbuz, S.
    Foley, P.
    [J]. AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2016, 57 : 40 - 41