Functional recovery in new mouse models of ALS/FTLD after clearance of TDP-43 pathology

被引:0
|
作者
Walker, A. [1 ]
Spiller, K. [1 ]
Ge, G. [1 ]
Zheng, A. [1 ]
Xu, Y. [1 ]
Zhou, M. [1 ]
Tripathy, K. [1 ]
Kwong, L. [1 ]
Trojanowski, J. [1 ]
Lee, V. [1 ]
机构
[1] Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
MTU11-44
引用
收藏
页码:208 / 209
页数:2
相关论文
共 50 条
  • [41] TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD
    Nag, Sukriti
    Yu, Lei
    Wilson, Robert S.
    Chen, Er-Yun
    Bennett, David A.
    Schneider, Julie A.
    NEUROLOGY, 2017, 88 (07) : 653 - 660
  • [42] TDP-43 pathology and cognition in ALS: A prospective clinicopathologic correlation study
    Prudlo, Johannes
    Koenig, Jochem
    Schuster, Christina
    Kasper, Elisabeth
    Buettner, Andreas
    Teipel, Stefan
    Neumann, Manuela
    NEUROLOGY, 2016, 87 (10) : 1019 - 1023
  • [43] Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice
    Ding, Xuebing
    Xiang, Zhi
    Qin, Chi
    Chen, Yongkang
    Tian, Haiyan
    Meng, Lin
    Xia, Danhao
    Liu, Han
    Song, Jia
    Fu, Jun
    Ma, Mingming
    Wang, Xuejing
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021, 9 (01)
  • [44] Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice
    Xuebing Ding
    Zhi Xiang
    Chi Qin
    Yongkang Chen
    Haiyan Tian
    Lin Meng
    Danhao Xia
    Han Liu
    Jia Song
    Jun Fu
    Mingming Ma
    Xuejing Wang
    Acta Neuropathologica Communications, 9
  • [45] Correlation of the phosphorylated TDP-43 pathology in the hippocampus and dementia of ALS patients
    Nagai, M.
    Kawanami, A.
    Yanagida, A.
    Nishiyama, K.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2017, 381 : 566 - 566
  • [46] NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility
    Amanda M. Gleixner
    Brandie Morris Verdone
    Charlton G. Otte
    Eric N. Anderson
    Nandini Ramesh
    Olivia R. Shapiro
    Jenna R. Gale
    Jocelyn C. Mauna
    Jacob R. Mann
    Katie E. Copley
    Elizabeth L. Daley
    Juan A. Ortega
    Maria Elena Cicardi
    Evangelos Kiskinis
    Julia Kofler
    Udai B. Pandey
    Davide Trotti
    Christopher J. Donnelly
    Nature Communications, 13
  • [47] Abnormal phosphorylation of ser409/410 of TDP-43 in FTLD-U and ALS
    Inukai, Yuki
    Nonaka, Takashi
    Arai, Tetsuaki
    Yoshida, Mari
    Hashizume, Yoshio
    Beach, Thomas G.
    Buratti, Emanuele
    Baralle, Francisco E.
    Akiyama, Haruhiko
    Hisanaga, Shin-ichi
    Hasegawa, Masato
    FEBS LETTERS, 2008, 582 (19) : 2899 - 2904
  • [48] Transgenic Rat Overexpressing TDP-43, an Animal Model to study FTLD-U and ALS
    Koza, Paulina
    Klejman, Agata
    Gorkiewicz, Tomasz
    Knapska, Ewelina
    Kaczmarek, Leszek
    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2012, 33 : 52 - 53
  • [49] NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility
    Gleixner, Amanda M.
    Verdone, Brandie Morris
    Otte, Charlton G.
    Anderson, Eric N.
    Ramesh, Nandini
    Shapiro, Olivia R.
    Gale, Jenna R.
    Mauna, Jocelyn C.
    Mann, Jacob R.
    Copley, Katie E.
    Daley, Elizabeth L.
    Ortega, Juan A.
    Cicardi, Maria Elena
    Kiskinis, Evangelos
    Kofler, Julia
    Pandey, Udai B.
    Trotti, Davide
    Donnelly, Christopher J.
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [50] Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD
    Chevalier, Elodie
    Audrain, Mickael
    Ratnam, Monisha
    Ollier, Romain
    Fuchs, Aline
    Piorkowska, Kasia
    Pfeifer, Andrea
    Kosco-Vilbois, Marie
    Seredenina, Tamara
    Afroz, Tariq
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2024, 12 (01):