Voltammetric behaviour of ketorolac and its HPLC-EC determination in tablets.

被引：7
|
作者：
Squella, JA
Lemus, I
Sturm, JC
NunezVergara, LJ
机构：
[1] Bioelectrochemistry Laboratory, Fac. Chem. and Pharmaceutical Sci., University of Chile, Santiago 1
来源：
ANALYTICAL LETTERS | 1997年 / 30卷 / 03期
关键词：
voltammetry; HPLC; electrochemical detection; ketorolac;
D O I：
10.1080/00032719708001801
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Ketorolac is an antiinflammatory-analgesic agent that is oxidizable at the glassy carbon electrode. The voltammetric oxidation produces two well resolved pH-dependent peaks, that are overlapped at pH>10. Using this voltammetric response a HPLC procedure with electrochemical detection in order to quantify ketorolac in pharmaceutical dosage forms is presented. Furthermore comparative methods using UV spectrophotometry and HPLC with photodiode array detector were used.
引用
收藏
页码：553 / 564
页数：12
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