SEOM clinical guideline for the management of malignant melanoma (2017)

被引：12

作者：

Berrocal, A. ^{[1
]}

Arance, A. ^{[2
]}

Castellon, V. E. ^{[3
]}

de la Cruz, L. ^{[4
]}

Espinosa, E. ^{[5
]}

Cao, M. G. ^{[6
]}

Larriba, J. L. G. ^{[7
]}

Marquez-Rodas, I. ^{[8
]}

Soria, A. ^{[9
]}

Algarra, S. M. ^{[10
]}

机构：

[1] Consorcio Hosp Gen Univ Valencia, Med Oncol Serv, Avda Tres Cruces 2, Valencia 46014, Spain

[2] Hosp Clin Barcelona, Barcelona, Spain

[3] Hosp Torrecardenas, Almeria, Spain

[4] Complejo Hosp Reg Virgen Macaren, Seville, Spain

[5] Hosp Univ La Paz, Madrid, Spain

[6] Hosp Univ Quiron Dexeus, Barcelona, Spain

[7] Hosp Univ Clin San Carlos, Madrid, Spain

[8] Hosp Gen Univ Gregorio Maranon, Madrid, Spain

[9] Hosp Univ Ramon y Cajal, Madrid, Spain

[10] Clin Univ Navarra, Pamplona, Spain

来源：

CLINICAL & TRANSLATIONAL ONCOLOGY | 2018年 / 20卷 / 01期

关键词：

Melanoma; Metastatic; Adjuvant; Immunotherapy; B-RAF; OPEN-LABEL; HIGH-RISK; BRAF; IPILIMUMAB; NIVOLUMAB; SURVIVAL; PEMBROLIZUMAB; MULTICENTER; VEMURAFENIB; INTERFERON;

D O I：

10.1007/s12094-017-1768-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

All melanoma suspected patients must be confirmed histologically and resected. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon could be offered for patients with high-risk melanoma and in selected cases radiotherapy can be added. Metastatic melanoma treatment is guided by mutational BRAF status. BRAF wild type patients must receive anti-PD1 containing therapy and BRAF mutated patients BRAF/MEK inhibitors or anti-PD1 containing therapy. Up to 10 years follow up is reasonable for melanoma patients with dermatologic examinations and physical exams.

引用

页码：69 / 74

页数：6

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