SEOM clinical guideline for the management of malignant melanoma (2017)

被引:12
|
作者
Berrocal, A. [1 ]
Arance, A. [2 ]
Castellon, V. E. [3 ]
de la Cruz, L. [4 ]
Espinosa, E. [5 ]
Cao, M. G. [6 ]
Larriba, J. L. G. [7 ]
Marquez-Rodas, I. [8 ]
Soria, A. [9 ]
Algarra, S. M. [10 ]
机构
[1] Consorcio Hosp Gen Univ Valencia, Med Oncol Serv, Avda Tres Cruces 2, Valencia 46014, Spain
[2] Hosp Clin Barcelona, Barcelona, Spain
[3] Hosp Torrecardenas, Almeria, Spain
[4] Complejo Hosp Reg Virgen Macaren, Seville, Spain
[5] Hosp Univ La Paz, Madrid, Spain
[6] Hosp Univ Quiron Dexeus, Barcelona, Spain
[7] Hosp Univ Clin San Carlos, Madrid, Spain
[8] Hosp Gen Univ Gregorio Maranon, Madrid, Spain
[9] Hosp Univ Ramon y Cajal, Madrid, Spain
[10] Clin Univ Navarra, Pamplona, Spain
来源
CLINICAL & TRANSLATIONAL ONCOLOGY | 2018年 / 20卷 / 01期
关键词
Melanoma; Metastatic; Adjuvant; Immunotherapy; B-RAF; OPEN-LABEL; HIGH-RISK; BRAF; IPILIMUMAB; NIVOLUMAB; SURVIVAL; PEMBROLIZUMAB; MULTICENTER; VEMURAFENIB; INTERFERON;
D O I
10.1007/s12094-017-1768-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
All melanoma suspected patients must be confirmed histologically and resected. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon could be offered for patients with high-risk melanoma and in selected cases radiotherapy can be added. Metastatic melanoma treatment is guided by mutational BRAF status. BRAF wild type patients must receive anti-PD1 containing therapy and BRAF mutated patients BRAF/MEK inhibitors or anti-PD1 containing therapy. Up to 10 years follow up is reasonable for melanoma patients with dermatologic examinations and physical exams.
引用
收藏
页码:69 / 74
页数:6
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