Transient ischemic attack-like episodes without stroke-like lesions in MELAS

被引：7

作者：

Mitani, Tadahiro ^{[1
]}

Aida, Noriko ^{[2
]}

Tomiyasu, Moyoko ^{[3
]}

Wada, Takahito ^{[1
]}

Osaka, Hitoshi ^{[1
]}

机构：

[1] Kanagawa Childrens Med Ctr, Div Neurol, Minami Ku, Yokohama, Kanagawa 2328555, Japan

[2] Kanagawa Childrens Med Ctr, Div Radiol, Yokohama, Kanagawa, Japan

[3] Natl Inst Radiol Sci, Res Ctr Charged Particle Therapy, Chiba 260, Japan

来源：

PEDIATRIC RADIOLOGY | 2013年 / 43卷 / 10期

关键词：

MELAS; MR spectroscopy; Mitochondrium; Stroke-like episode; MAGNETIC-RESONANCE-SPECTROSCOPY;

D O I：

10.1007/s00247-013-2661-x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A stroke-like episode is a core symptom in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Proton magnetic resonance spectroscopy (H-1-MRS) is useful in the diagnosis of mitochondrial diseases. We report an 8-year-old girl with MELAS, presenting with a seizure and blindness. H-1-MRS showed a strikingly elevated lactate peak in the right occipital region, where no abnormal signals appeared on either T2-W or diffusion-weighted MRI. She recovered completely within a day. We describe this mild clinical condition with abnormal lactate peak in normal-appearing gray matter as a transient ischemic attack-like episode in MELAS.

引用

页码：1400 / 1403

页数：4

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