Penalized empirical likelihood for the sparse Cox regression model

The current penalized regression methods for selecting predictor variables and estimating the associated regression coefficients in the sparse Cox model are mainly based on partial likelihood. In this paper, a bias-corrected empirical likelihood method is proposed for the sparse Cox model in conjunction with appropriate penalty functions when the dimensionality of data is high. Theoretical properties of the resulting estimator for the large sample are proved. Simulation studies suggest that penalized empirical likelihood works better than partial likelihood in terms of selecting correct predictors without introducing more model errors. The well-known primary biliary cirrhosis data set is used to illustrate the proposed penalized empirical likelihood method. (C) 2018 Elsevier B.V. All rights reserved.