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NOV-002, a glutathione disulfide mimetic, is a pleiotropic modulator of cellular redox balance

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作者：
Townsend, Danyelle M. [1 ]
机构：
[1] Med Univ S Carolina, Dept Pharmaceut & Biomed Sci, Charleston, SC 29425 USA
来源：
BIOMEDICINE & PHARMACOTHERAPY | 2008年 / 62卷 / 08期
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D O I：
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中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
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页码：514 / 514
页数：1
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  • [1] NOV-002, a glutathione disulfide mimetic, is a pleiotropic modulator of cellular redox balance
    Tew, Kenneth D.
    He, Lin
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    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2008, 62 (07) : 427 - 427
  • [2] NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance
    Townsend, Danyelle M.
    He, Lin
    Hutchens, Steven
    Garrett, Tracy E.
    Pazoles, Christopher J.
    Tew, Kenneth D.
    [J]. CANCER RESEARCH, 2008, 68 (08) : 2870 - 2877
  • [3] NOV-002, a mimetic of glutathione disulfide
    Townsend, Danyelle M.
    Pazoles, Christopher J.
    Tew, Kenneth D.
    [J]. EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2008, 17 (07) : 1075 - 1083
  • [4] Pharmacology of a mimetic of glutathione disulfide, NOV-002
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    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2009, 63 (02) : 75 - 78
  • [5] Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic
    Uys, J. D.
    Manevich, Y.
    DeVane, L. C.
    He, L.
    Garret, T. E.
    Pazoles, C. J.
    Tew, K. D.
    Townsend, D. M.
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2010, 64 (07) : 493 - 498
  • [6] In vivo pharmacokinetic and pharmacodynamic behavior of NOV-002, a redox-modulating glutathione disulfide mimetic
    Townsend, Danyelle
    He, Lin
    Hutchens, Steven
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    [J]. CANCER RESEARCH, 2009, 69
  • [7] Protective effects of a glutathione disulfide mimetic (NOV-002) against cisplatin induced kidney toxicity
    Jenderny, Sara
    Lin, He
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    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2010, 64 (01) : 73 - 76
  • [8] The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide-induced hematopoietic and immune suppression by reducing oxidative stress
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    Zidan, Abdel-Aziz
    Pazoles, Christopher J.
    Montero, Alberto J.
    Zhou, Daohong
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2012, 52 (09) : 1560 - 1568
  • [9] NOV-002, a redox-modulating glutathione disulfide mimetic, leads to calcium influx and nitric oxide generation through eNOS activation in myeloid cells
    Manevich, Yefim
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    [J]. CANCER RESEARCH, 2009, 69
  • [10] Mechanism of action studies of NOV-002, a novel glutathione disulfide anticancer drug.
    Townsend, DM
    Kemppa, E
    Pazoles, C
    Tew, KD
    [J]. CLINICAL CANCER RESEARCH, 2005, 11 (24) : 9083S - 9083S
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