Serum sickness-like syndrome due to mosquito bite

被引:0
|
作者
Gaig, P [1 ]
García-Ortega, P [1 ]
Enrique, E [1 ]
Benet, A [1 ]
Bartolomé, B [1 ]
Palacios, R [1 ]
机构
[1] Univ Rovira & Virgili, Allergy Unit, Hosp Joan 23, Dept Med, Tarragona 43007, Spain
来源
JOURNAL OF INVESTIGATIONAL ALLERGOLOGY & CLINICAL IMMUNOLOGY | 1999年 / 9卷 / 03期
关键词
leucocytoclastic vasculitis; mosquito bite; serum sickness;
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Local inflammatory reactions at the site of a mosquito bite are frequent. immediate systemic reactions have occasionally been reported The first case of a patient with relapsing episodes of a serum sickness-like syndrome following mosquito bites is reported herein. A 62-year-old patient came to the emergency room complaining of sudden malaise, chills, fever, headache, cervical lymph node enlargement arthromyalgia, generalized purpura and leukopenia 6 h after a mosquito bite. He had experienced multiple similar episodes in the last 20 years, also following mosquito bites infectious and autoimmune diseases were ruled out Serum IgE was 9,102 kU/l. Prick test of whole-body Culex pipiens extract was positive. Specific IgE to Aedes communis was 2.25 kU/l. SDS-PAGE immunoblotting of the patient's serum with whole-body C. pip; lens extract revealed 43 and 17 kDa IgG-binding proteins and 22 and 17 kDa IgE-binding proteins, neither of which were found with control sera. Skin biopsy was consistent with leukocytoclastic vasculitis. The presence of both mosquito-specific IgE and IgG in the patient's serum suggest a possible cooperative immune response leading to clinical manifestations of serum sickness.
引用
收藏
页码:190 / 192
页数:3
相关论文
共 50 条
  • [21] Serum sickness-like reaction due to Infliximab reintroduction during pregnancy
    Grosen, Anne
    Julsgaard, Mette
    Christensen, Lisbet Ambrosius
    JOURNAL OF CROHNS & COLITIS, 2013, 7 (05): : E191 - E191
  • [22] Serum Sickness-Like Reaction with Clarithromycin
    Sohail, Muhammad Adnan
    Nasir, Junaid
    Ikram, Umaira
    Genese, Thomas
    JOURNAL OF HOSPITAL MEDICINE, 2011, 6 (04) : 231 - 232
  • [23] Severe serum sickness-like syndrome after omalizumab therapy for asthma
    Pilette, Charles
    Coppens, Nathalie
    Houssiau, Frederic A.
    Rodenstein, Daniel O.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (04) : 972 - 973
  • [25] Serum Sickness and Serum Sickness-Like Reactions Presenting to Pediatric Hospital
    Friedman, Nir
    Test, Gidon
    Scolnik, Dennis
    CLINICAL PEDIATRICS, 2024,
  • [26] Serum sickness-like reaction from cefaclor
    Classen, A.
    Dieks, J-K
    Henneke, M.
    Lippert, U.
    ALLERGY, 2015, 70 : 546 - 546
  • [27] Serum sickness-like reaction associated with griseofulvin
    Colton, RL
    Amir, J
    Mimouni, M
    Zeharia, A
    ANNALS OF PHARMACOTHERAPY, 2004, 38 (04) : 609 - 611
  • [28] Serum sickness-like reaction due to amoxicillin/clavulanic acid in two children
    Celik, Kulhas, I
    Misirlioglu, Dibek E.
    Hurmuzlu, S.
    Kocabas, C.
    ALLERGY, 2017, 72 : 696 - 697
  • [29] Cefaclor and serum sickness-like reaction - Reply
    Kelsey, DK
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 276 (12): : 950 - 951
  • [30] SERUM SICKNESS-LIKE SYNDROME TO MINOCYCLINE PRESENTING AS URTICARIA WITH NORMAL SERUM COMPLEMENT LEVELS
    Parrish, C.
    Wong, A.
    Thobani, S.
    Li, M.
    Scott, L.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2013, 111 (05) : A77 - A77