Bio-inspired mineral growth on porous spherulitic textured poly(L-lactic acid)/bioactive glass composite scaffolds

被引：4
|
作者：
Ghosh, Satyabrata [1 ,2 ]
Reis, Rui L. [1 ,2 ]
Mano, Joao F. [1 ,2 ]
机构：
[1] Univ Minho, Dept Polymer Engn, 3Bs Res Grp Biomat Biodegradables & Biomimet, P-4710057 Braga, Portugal
[2] Pt Govt Associated Lab, IBB Inst Biotechnol & Bioengn, Braga, Portugal
来源：
ADVANCED ENGINEERING MATERIALS | 2008年 / 10卷 / 08期
关键词：
D O I：
10.1002/adem.200700360
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
It has been shown that texture can strongly influence the adhesion, orientation and proliferation of cells onto the surface of biomaterials. Additionally, it is possible to imprint micrometer level textures throughout the scaffolds by melt compounding PLLA/polyethylene oxide (PEO) blend, quenching followed by leaching of PEO in water. The objective of this work is to verify how the texture in 3D porous PLLA/Bioglass®composite scaffolds may influence the precipitation of apatite in vitro. © 2008 WILEY-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：B18 / B22
页数：5
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