Assessment of Aloe vera (L.) genotoxic potential on Escherichia coli and plasmid DNA

被引：21
|
作者：
Paes-Leme, AA [1 ]
Motta, ES [1 ]
De Mattos, JCP [1 ]
Dantas, FJS [1 ]
Bezerra, RJAC [1 ]
Caldeira-De-Araujo, A [1 ]
机构：
[1] Univ Fed Rio de Janeiro, Inst Biol Roberto Alcantara Gomes, Dept Biofis & Biometr, BR-20551030 Rio De Janeiro, Brazil
来源：
JOURNAL OF ETHNOPHARMACOLOGY | 2005年 / 102卷 / 02期
关键词：
Aloe vera; babosa; UVA light; Escherichia coli; genotoxic potential;
D O I：
10.1016/j.jep.2005.06.013
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Aloe vera is a tropical plant, known in Brazil as babosa and several reputable suppliers produce a stabilized aloe gel for topic use. Since people use Aloe vera topically, they could be exposed to solar ultraviolet light in addition and it might cause a cross damage effect between these agents. The aim of this work was to investigate the biological effects of Aloe vera pulp extract, associated or not to UVA radiation, on Escherichia coli-deficient repair mutants and plasmid DNA, in order to test its genotoxic potential. Data obtained from analysis of survival fractions, bacterial transformation and agarose gel electrophoresis suggest that Aloe vera has' genotoxic properties, but it seems not to be able to damage the cell membrane. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
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页码：197 / 201
页数：5
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