Multiple routes for the synthesis of N-acyl sulfonamide-bridged nucleosides

被引：0
|
作者：
Johnson, DC [1 ]
Widlanski, TS [1 ]
机构：
[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA
来源：
SYNTHESIS-STUTTGART | 2002年 / 06期
关键词：
sulfonamide; sulfonimide; nucleosides; sulfonamide dianion; protecting groups;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Methods are described for the synthesis of uridine nucleoside derivatives containing an alpha-3"-methylenesulfonamide functionality. Several monomers possessing this functionality in both ribo- and deoxyribo-forms are detailed. Use of these monomers to construct the first N-acylsulfonamide-bridged dinucleoside is also described.
引用
收藏
页码：809 / 815
页数：7
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