1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol

被引：1

作者：

Xu, Jian ^{[1
]}

Xu, Hao ^{[1
]}

Quan, Ji-cai ^{[1
]}

Sha, Fei ^{[1
]}

Yao, Cheng ^{[1
]}

机构：

[1] Nanjing Univ Technol, Coll Sci, Nanjing 210009, Peoples R China

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷

关键词：

D O I：

10.1107/S1600536808041068

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compound, C11H12O2, is an intermediate in the synthesis of Varenicline, a nicotinic receptor partial agonist used to treat smoking addiction. In the crystal structure, there is an intramolecular O-H center dot center dot center dot O hydrogen bond that generates an S(5) ring motif. Intermolecular O-H center dot center dot center dot O hydrogen bonds form centrosymmetric dimers and also link these dimers into chains along the a axis.

引用

页码：O79 / U1958

页数：9

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