Biocompatibility and biodegradability of 2D materials: graphene and beyond

被引：162
|
作者：
Martin, Cristina [1 ]
Kostarelos, Kostas [2 ,3 ]
Prato, Maurizio [4 ,5 ,6 ]
Bianco, Alberto [1 ]
机构：
[1] Univ Strasbourg, CNRS, Immunol Immunopathol & Therapeut Chem, F-67000 Strasbourg, France
[2] Univ Manchester, Natl Graphene Inst, Nanomed Lab, Manchester, Lancs, England
[3] Univ Manchester, Fac Biol Med & Hlth, Manchester, Lancs, England
[4] Univ Trieste, Dept Chem & Pharmaceut Sci, I-34127 Trieste, Italy
[5] CIC BiomaGUNE, Carbon Bionanotechnol Lab, San Sebastian 20009, Spain
[6] Ikerbasque, Basque Fdn Sci, Bilbao 48013, Spain
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 39期
基金：
英国工程与自然科学研究理事会;
关键词：
BLACK PHOSPHORUS NANOSHEETS; MOS2; NANOSHEETS; OXIDE SHEETS; CYTOTOXICITY; NANOMATERIALS; DEGRADATION; TOXICITY; DELIVERY; CELLS; PRISTINE;
D O I：
10.1039/c9cc01205b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The potential risks associated with two-dimensional (2D) nanomaterials may cause serious concerns about their real applications and impact in biological systems. In addition, the demonstration of biodegradability of these flat nanomaterials is essential in living organisms. Here, we summarise the state-of-the-art in the field of biocompatibility and biodegradability of graphene-related materials (such as 2D materials like MoS2, BN or WS2). The impact of chemical functionalisation on the potential control of the biodegradability profile of these structures is also discussed.
引用
收藏
页码：5540 / 5546
页数：7
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