Balloon liver cells forming Mallory-Denk-bodies are progenitor cells

被引：3
|
作者：
French, S. W. [1 ]
Vitocruz, E. [1 ]
French, B. A. [1 ]
机构：
[1] Harbor UCLA Med Ctr, Dept Pathol, Torrance, CA 90509 USA
来源：
EXPERIMENTAL AND MOLECULAR PATHOLOGY | 2013年 / 95卷 / 01期
关键词：
Mallory-Denk bodies (MDBs); Toll-like receptor 4 (TLR4); Integrin alpha 6 (CD49f); Progenitor cells; Tumor-initiating stem-like cells (TISC); BODY FORMATION; HEPATOCELLULAR-CARCINOMA; MOUSE MODEL; PATHOGENESIS; PRENEOPLASIA; ALCOHOL; FAT10;
D O I：
10.1016/j.yexmp.2013.06.001
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Previous studies on both human and mice livers showed MDB formation in both drug hepatitis and hepatocellular carcinoma. Using the drug hepatitis mouse model of MDB formation, numerous markers for progenitor cells were found in the cells forming MDBs. In current study, using the drug hepatitis mouse model, we found that the MDB forming cells expressed two additional progenitor cell markers. These markers were CD49f and TLR4. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码：117 / 120
页数：4
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