Overexpression of MRP4 or MRP5 confers resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine

被引：1
|
作者：
Adema, Auke D.
Floor, Karijn
Smid, Kees
Honeywell, Richard J.
Peters, Godefridus J.
机构：
来源：
MOLECULAR CANCER THERAPEUTICS | 2009年 / 8卷 / 12期
关键词：
D O I：
10.1158/1535-7163.TARG-09-B65
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B65
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Interaction of Oxazaphosphorines with Multidrug Resistance-Associated Protein 4 (MRP4)
    Jing Zhang
    Ka-Yun Ng
    Paul C. Ho
    The AAPS Journal, 2010, 12 : 300 - 308
  • [42] Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro
    Norris, MD
    Smith, J
    Tanabe, K
    Tobin, P
    Flemming, C
    Scheffer, GL
    Wielinga, L
    Cohn, SL
    London, WB
    Marshall, GM
    Allen, JD
    Haber, M
    MOLECULAR CANCER THERAPEUTICS, 2005, 4 (04) : 547 - 553
  • [43] Chalcogenopyrylium Dyes as Differential Modulators of Organic Anion Transport by Multidrug Resistance Protein 1 (MRP1), MRP2, and MRP4
    Myette, Robert L.
    Conseil, Gwenaelle
    Ebert, Sean P.
    Wetzel, Bryan
    Detty, Michael R.
    Cole, Susan P. C.
    DRUG METABOLISM AND DISPOSITION, 2013, 41 (06) : 1231 - 1239
  • [44] Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4
    Hardy, David
    Bill, Roslyn M.
    Jawhari, Anass
    Rothnie, Alice J.
    SLAS DISCOVERY, 2019, 24 (10) : 1000 - 1008
  • [45] A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5)
    Ravna, Aina Westrheim
    Sylte, Ingebrigt
    Sager, Georg
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (11) : 2557 - 2567
  • [46] Expression of messenger RNA encoding for multidrug resistance protein 5 (MRP5) in the human prostate
    Kuethe, A
    Stief, CG
    Ueckert, S
    Truss, MC
    Jonas, U
    JOURNAL OF UROLOGY, 2003, 169 (04): : 283 - 284
  • [47] ABCC4/MRP4和ABCC5/MRP5基因在NK/T细胞淋巴瘤的表达及与临床疗效的关系
    李汝平
    韩丽娟
    张旭东
    张明智
    胡腾鹏
    秦贝贝
    文建国
    中国癌症杂志, 2014, 24 (01) : 8 - 14
  • [48] Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia
    van der Kolk, DM
    de Vries, EGE
    Noordhoek, L
    van den Berg, E
    van der Pol, MA
    Müller, M
    Vellenga, E
    LEUKEMIA, 2001, 15 (10) : 1544 - 1553
  • [49] Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia
    DM van der Kolk
    EGE de Vries
    L Noordhoek
    E van den Berg
    MA van der Pol
    M Müller
    E Vellenga
    Leukemia, 2001, 15 : 1544 - 1553
  • [50] Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies
    Scheffer, GL
    Kool, M
    Heijn, M
    de Haas, M
    Pijnenborg, ACLM
    Wijnholds, J
    van Helvoort, A
    de Jong, MC
    Hooijberg, JH
    Mol, CAAM
    van der Linden, M
    de Vree, JML
    van der Valk, P
    Elferink, RPJO
    Borst, P
    Scheper, RJ
    CANCER RESEARCH, 2000, 60 (18) : 5269 - 5277
12345