Toonamicronoids A-D, four new B-seco-limonoids from Toona microcarpa

被引：6

作者：

Zhang, Ling ^{[1
,2
]}

Xia, Jianjun ^{[1
]}

Yang, Jianyun ^{[1
]}

Zhu, Long ^{[1
]}

Tang, Danyu ^{[1
]}

Ma, Ji ^{[2
]}

Zhao, Yingliang ^{[1
]}

Zeng, Xiaoying ^{[1
]}

Qiu, Minghua ^{[2
]}

机构：

[1] R&D Ctr China Tobacco Yunnan Ind Co Ltd, Kunming 650202, Yunnan, Peoples R China

[2] Chinese Acad Sci, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2019年 / 31卷

关键词：

Toona microcarpa; Toonamicronoids A-D; Limonoid; Identification; Cytotoxicity; CILIATA;

D O I：

10.1016/j.phytol.2019.04.010

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new B-seco-limonoids, toonamicronoids A-D (1-4), together with four known ones, toonaciliatin H-J (5-7), and toonacilianin A (8), were isolated from Toona microcarpa. Their structures were identified on the basis of ESIMS, HREIMS and 1D/2D NMR analysis. Compounds 1 and 4 showed moderate cytotoxicities against HL-60 with the IC(50)values of 17.3 +/- 1.5 and 22.7 +/- 1.9 mu M, respectively.

引用

页码：225 / 228

页数：4

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