Label-free Detection of Nucleic Acid Composition within DNA Strands using Surface-enhanced Raman Spectroscopy

被引:0
|
作者
Freeman, Lindsay M. [1 ]
Pang, Lin [1 ]
Fainman, Yeshaiahu [1 ]
机构
[1] Univ Calif San Diego, Dept Elect & Comp Engn, 9500 Gilman Dr, La Jolla, CA 92093 USA
关键词
SCATTERING;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We demonstrate label-free detection of the composition of a single strand of DNA using surface-enhanced Raman spectroscopy in which DNA is linearized to plasmonic surfaces and hundreds of Raman spectra are acquired and statistically analyzed.
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Extracellular Vesicle Identification Using Label-Free Surface-Enhanced Raman Spectroscopy: Detection and Signal Analysis Strategies
    Shin, Hyunku
    Seo, Dongkwon
    Choi, Yeonho
    [J]. MOLECULES, 2020, 25 (21):
  • [32] Label-free surface-enhanced Raman spectroscopy for detection of colorectal cancer and precursor lesions using blood plasma
    Feng, Shangyuan
    Wang, Wenbo
    Tai, Isabella T.
    Chen, Guannan
    Chen, Rong
    Zeng, Haishan
    [J]. BIOMEDICAL OPTICS EXPRESS, 2015, 6 (09): : 3494 - 3502
  • [33] Advances in Label-Free Glucose Detection Using Self-Assembled Nanoparticles and Surface-Enhanced Raman Spectroscopy
    Jiang, Shen
    Li, Qiuyun
    Wu, Guangrun
    Mu, Xuming
    Wang, Xiaotong
    Wang, Yunpeng
    Wu, Yanli
    Wu, Jing
    Li, Yang
    [J]. ANALYTICAL CHEMISTRY, 2024, 96 (28) : 11533 - 11541
  • [34] Label-free detection of binary mixtures of proteins using surface-enhanced Raman scattering
    Zhou, Zhen
    Han, Xiaoxia
    Huang, Genin Gary
    Ozaki, Yukihiro
    [J]. JOURNAL OF RAMAN SPECTROSCOPY, 2012, 43 (06) : 706 - 711
  • [35] Label-Free Detection of Native Proteins by Surface-Enhanced Raman Spectroscopy Using Iodide-Modified Nanoparticles
    Xu, Li-Jia
    Zong, Cheng
    Zheng, Xiao-Shan
    Hu, Pei
    Feng, Jia-Min
    Ren, Bin
    [J]. ANALYTICAL CHEMISTRY, 2014, 86 (04) : 2238 - 2245
  • [36] Label-free serum detection of Trichinella spiralis using surface-enhanced Raman spectroscopy combined with multivariate analysis
    Li, Jian
    Ding, Jing
    Liu, Xiaolei
    Tang, Bin
    Bai, Xue
    Wang, Yang
    Li, Shicun
    Wang, Xuelin
    [J]. ACTA TROPICA, 2020, 203
  • [37] New Insights into Surface-Enhanced Raman Spectroscopy Label-Free Detection of DNA on Ag°/TiO2 Substrate
    He, Lijie
    Langlet, Michel
    Bouvier, Pierre
    Calers, Christophe
    Pradier, Claire-Marie
    Stambouli, Valerie
    [J]. JOURNAL OF PHYSICAL CHEMISTRY C, 2014, 118 (44): : 25658 - 25670
  • [38] A surface-enhanced Raman spectroscopy substrate for highly sensitive label-free immunoassay
    Zhang, Ming-Liang
    Yi, Chang-Qing
    Fan, Xia
    Peng, Kui-Qing
    Wong, Ning-Bew
    Yang, Meng-Su
    Zhang, Rui-Qin
    Lee, Shuit-Tong
    [J]. APPLIED PHYSICS LETTERS, 2008, 92 (04)
  • [39] Picoanalysis of Drugs in Biofluids with Quantitative Label-Free Surface-Enhanced Raman Spectroscopy
    Turzhitsky, Vladimir
    Zhang, Lei
    Horowitz, Gary L.
    Vitkin, Edward
    Khan, Umar
    Zakharov, Yuri
    Qiu, Le
    Itzkan, Irving
    Perelman, Lev T.
    [J]. SMALL, 2018, 14 (47)
  • [40] Label-free serum ribonucleic acid analysis for colorectal cancer detection by surface-enhanced Raman spectroscopy and multivariate analysis
    Chen, Yanping
    Chen, Gang
    Feng, Shangyuan
    Pan, Jianji
    Zheng, Xiongwei
    Su, Ying
    Chen, Yan
    Huang, Zufang
    Lin, Xiaoqian
    Lan, Fenghua
    Chen, Rong
    Zeng, Haishan
    [J]. JOURNAL OF BIOMEDICAL OPTICS, 2012, 17 (06)