New cadinane sesquiterpenoids from the basidiomycetous fungus Pholiota sp.

被引:4
|
作者
Lin, Jie [1 ]
Wang, Renlei [1 ]
Xu, Guohua [1 ]
Ding, Zhengfeng [1 ]
Zhu, Xueshen [1 ]
Liu, Xingzhong [2 ]
Zou, Jian [3 ]
Chen, Guodong [3 ]
Li, Li [4 ,5 ]
Liu, Ling [2 ]
机构
[1] Jiangsu Second Normal Univ, Coll Life Sci & Chem, Jiangsu Key Lab Biofunct Mol, 77 West Beijing Rd, Nanjing 210013, Jiangsu, Peoples R China
[2] Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100101, Peoples R China
[3] Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
[4] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
[5] Peking Union Med Coll, Beijing 100050, Peoples R China
基金
中国国家自然科学基金;
关键词
CORDYCEPS-COLONIZING ISOLATE; HYPERSENSITIVITY PNEUMONITIS; A-D; DERIVATIVES;
D O I
10.1039/c6ra22448b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Five new cadinane sesquiterpenoids, pholiotins A-E (1-5), and three known compounds, 11-hydroxy-1(10)-valencen-2-one (6), 8,11-dihydroxy-1(10)-eremophilen-2-one (7) and durgamone (8), were isolated from the crude extract of Pholiota sp. Their structures were established on the basis of extensive spectroscopic analysis. Their absolute configurations were determined by X-ray diffraction, the Snatzke's method and electronic circular dichroism (ECD) calculations. All isolates were tested for antifungal activity.
引用
收藏
页码:112527 / 112533
页数:7
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