Sesquiterpenoids isolated from an endophyte fungus Diaporthe sp.

被引：23

作者：

Chen, Chao-Jun ^{[1
]}

Liu, Xian-Xian ^{[1
]}

Zhang, Wen-Jing ^{[1
]}

Zang, Le-Yun ^{[1
]}

Wang, Gang ^{[1
]}

Ng, Seik Weng ^{[2
]}

Tan, Ren-Xiang ^{[1
]}

Ge, Hui-Ming ^{[1
]}

机构：

[1] Nanjing Univ, Inst Funct Biomol, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Jiangsu, Peoples R China

[2] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

来源：

RSC ADVANCES | 2015年 / 5卷 / 23期

关键词：

D O I：

10.1039/c4ra13136c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ten new sesquiterpenoids including six brasilane-type sesquiterpenoids, diaporols J-O (1-6), a 3,6-cycloprecapnellane sesquiterpenoid, diaporol P (7), and three drimane sesquiterpenoids, diaporols Q-S (8-10) were isolated from Diaporthe sp., an endophytic fungus associated with the leaves of Rhizophora stylosa collected in Hainan Province, China. The structures of these compounds were elucidated by extensive analysis of NMR, MS, CD spectra and single crystal X-ray diffraction. Among them, compound 9 exhibited moderate cytotoxicity against the SW480 cell line with an IC50 value of 8.72 +/- 1.32 mu M.

引用

页码：17559 / 17565

页数：7

共 50 条

[1] Sesquiterpenoids from the Mangrove-Derived Endophytic Fungus Diaporthe sp.
Zang, Le Yun
Wei, Wei
Guo, Ye
Wang, Ting
Jiao, Rui Hua
Ng, Seik Weng
Tan, Ren Xiang
Ge, Hui Ming
JOURNAL OF NATURAL PRODUCTS, 2012, 75 (10): : 1744 - 1749
[2] Sesquiterpenoids and meroterpenoids from a mangrove derived fungus Diaporthe sp. SCSIO 41011
Luo, Xiao-Wei
Chen, Chun-Mei
Li, Kun-Long
Lin, Xiu-Ping
Gao, Cheng-Hai
Zhou, Xue-Feng
Liu, Yong-Hong
NATURAL PRODUCT RESEARCH, 2021, 35 (02) : 282 - 288
[3] Azaphilones from the Endophyte Diaporthe sp. and Their Toxicity
Huang, Fangfang
Lin, Xiao
Lu, Quanyi
CHEMISTRY & BIODIVERSITY, 2022, 19 (11)
[4] Isochromophilones from an endophytic fungus Diaporthe sp.
Zang, Le-Yun
Wei, Wei
Wang, Ting
Guo, Ye
Tan, Ren-Xiang
Ge, Hui-Ming
NATURAL PRODUCTS AND BIOPROSPECTING, 2012, 2 (03): : 117 - 120
[5] Isochromophilones from an endophytic fungus Diaporthe sp.
Le-Yun Zang
Wei Wei
Ting Wang
Ye Guo
Ren-Xiang Tan
Hui-Ming Ge
Natural Products and Bioprospecting, 2012, 2 (3) : 117 - 120
[6] Cyclofarnesane sesquiterpenoids from the fungus Sanghuangporus sp.
Rajachan, Oue-artorn
Sangdee, Aphidech
Kanokmedhakul, Kwanjai
Tontapha, Sarawut
Amornkitbamrung, Vittaya
Kanokmedhakul, Somdej
PHYTOCHEMISTRY LETTERS, 2020, 37 : 17 - 20
[7] Antimycobacterial pimarane diterpenes from the fungus Diaporthe sp.
Dettrakul, S
Kittakoop, P
Isaka, M
Nopichai, S
Suyarnsestakorn, C
Tanticharoen, M
Thebtaranonth, Y
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (07) : 1253 - 1255
[8] Caryophyllene sesquiterpenoids from the endophytic fungus, Pestalotiopsis sp.
Liu, Yi
Yang, Ming-Hua
Wang, Xiao-Bing
Li, Tian-Xiao
Kong, Ling-Yi
FITOTERAPIA, 2016, 109 : 119 - 124
[9] Diaporthe sinensis, a new fungus from Amaranthus sp. in China
Feng, Xiao-Xiao
Chen, Jia-Jie
Wang, Guo-Rong
Cao, Ting-Ting
Zheng, Yong-Li
Zhang, Chu-Long
PHYTOTAXA, 2019, 425 (05) : 259 - 268
[10] Sesquiterpenoids from Fusarium sp., an Endophytic Fungus in Agriminia pilosa
Shan, Wei-Guang
Chen, Xiao-Xiao
Ying, You-Min
Zhan, Zha-Jun
HELVETICA CHIMICA ACTA, 2011, 94 (07) : 1254 - 1259

← 1 2 3 4 5 →