Mammalian Kruppel-like transcription factors: more than just a pretty finger

被引：264
|
作者：
Turner, J [1 ]
Crossley, M [1 ]
机构：
[1] Univ Sydney, Dept Biochem, Sydney, NSW 2006, Australia
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1999年 / 24卷 / 06期
关键词：
D O I：
10.1016/S0968-0004(99)01406-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The transcription factor SP1 contains three Kruppel-like zinc fingers. Recently, several related proteins, including erythroid, lung and gut-enriched Kruppel-like factors, have been identified. Together with SP1, these proteins form a sizeable family of transcription factors that share homology in their zinc-finger domains but differ elsewhere. Analysis of these differences is illuminating specific mechanisms by which transcription is regulated.
引用
收藏
页码：236 / 241
页数：6
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