Kruppel-like transcription factors and control of pluripotency

被引：42
|
作者：
Bourillot, Pierre-Yves
Savatier, Pierre [1 ]
机构：
[1] INSERM, U846, F-69500 Bron, France
来源：
BMC BIOLOGY | 2010年 / 8卷
关键词：
STEM-CELL DIFFERENTIATION; SELF-RENEWAL; MOUSE;
D O I：
10.1186/1741-7007-8-125
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Recent papers have demonstrated a role for Kruppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.
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页数：3
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