The Excessive Use of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease

被引:12
|
作者
Izquierdo Alonso, Jose Luis [1 ]
Rodriguez Glez-Moro, Jose Miguel [2 ]
机构
[1] Hosp Univ Guadalajara, Serv Neumol, Guadalajara, Spain
[2] Hosp Gen Gregorio Maranon, Serv Neumol, Madrid, Spain
来源
ARCHIVOS DE BRONCONEUMOLOGIA | 2012年 / 48卷 / 06期
关键词
Chronic obstructive pulmonary disease (COPD); Inhaled corticosteroids; Efficacy; Safety; FLUTICASONE PROPIONATE/SALMETEROL 250/50; METERED-DOSE INHALER; MYOCARDIAL-INFARCTION; COPD EXACERBATIONS; DOUBLE-BLIND; RISK; BUDESONIDE; SALMETEROL; BUDESONIDE/FORMOTEROL; PROPIONATE;
D O I
10.1016/j.arbres.2012.01.002
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Despite the fact that the recommendations of the main clinical guidelines have restricted the indications for inhaled corticosteroids in chronic obstructive pulmonary disease (COPD), currently more than 80% of patients are receiving this treatment in Spain, mostly with high doses. A detailed review of the literature does not justify the use of these high doses, a position that agrees with the recommendations of the FDA. A re-evaluation of their safety, the consistency of the data on their efficacy showing similar results with moderate doses and a better patient selection require the use of this treatment in COPD patients to be reconsidered. (C) 2011 SEPAR. Published by Elsevier Espana, S.L. All rights reserved.
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页码:207 / 212
页数:6
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