Oral MEK1/MEK2 inhibitor trametinib (GSK1120212) in combination with pemetrexed for KRAS-mutant and wild-type (WT) advanced non-small cell lung cancer (NSCLC): A phase I/Ib trial.

被引:0
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作者
Kelly, Karen
Mazieres, Julien
Leighl, Natasha B.
Barlesi, Fabrice
Zalcman, Gerard
Gordon, Michael S.
Reckamp, Karen L.
Gandara, David R.
Gomez-Roca, Carlos Alberto
Bennouna, Jaafar
Cho, Byoung Chul
Park, Keunchil
Infante, Jeffrey R.
Richards, Donald A.
Wu, Yuehui
Schramek, Daniel J.
Cox, Donna S.
Gardner, Olivia S.
Peddareddigari, Vijay Gopal Reddy
Blumenschein, George R.
机构
[1] UC Davis Comprehens Canc Ctr, Div Hematol & Oncol, Sacramento, CA USA
[2] Hop Larrey CHU Toulouse, Toulouse, France
[3] Princess Margaret Canc Ctr, Toronto, ON, Canada
[4] Aix Marseille Univ, Hop Nord, Assistance Publ Hop Marseille, Marseille, France
[5] Caen Univ Hosp, Caen, France
[6] Pinnacle Oncol Hematol, Scottsdale, AZ USA
[7] City Hope Comprehens Canc Ctr, Duarte, CA USA
[8] Univ Calif Davis, Ctr Comprehens Canc, Sacramento, CA 95817 USA
[9] Inst Claudius Regaud, Toulouse, France
[10] Inst Cancerol Ouest, Nantes, France
[11] Yonsei Univ, Coll Med, Seoul, South Korea
[12] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Seoul, South Korea
[13] Sarah Cannon Res Inst, Nashville, TN USA
[14] Tennessee Oncol, Nashville, TN USA
[15] Texas Oncol, Houston, TX USA
[16] GlaxoSmithKline, Collegeville, PA USA
[17] Univ Texas MD Anderson Canc Ctr, Dept Thorac Head & Neck Med Oncol, Houston, TX 77030 USA
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
8027
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页数:1
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