Synthesis of Chiral 1,2-Dihydronaphtho[2,1-b]furans by Organocatalytic Domino Reactions Catalyzed with Multiple Catalysis

被引：12

作者：

Pan, Jin-Yun ^{[1
]}

Li, Xin-Sheng ^{[1
]}

Xu, Dong-Cheng ^{[1
]}

Xie, Jian-Wu ^{[1
]}

机构：

[1] Zhejiang Normal Univ, Dept Chem & Life Sci, Jinhua 321004, Peoples R China

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2013年 / 66卷 / 11期

基金：

中国国家自然科学基金;

关键词：

MICHAEL REACTION; CYCLOPHANES; PHOTOCYCLIZATION; BENZOFURANS; ACCESS; ETHERS;

D O I：

10.1071/CH13317

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A chiral multiple catalysis with two chiral units has been proved effective in the domino Friedel-Crafts alkylation of -naphthols with -bromonitroalkenes. This novel and efficient domino reaction affords chiral 1,2-dihydronaphtho[2,1-b]furans in good to high yields and enantioselectivities (up to 93% yield, 91% enantiomeric excess).

引用

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页码：1415 / 1421

页数：7

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