Exercise-related complications in sickle cell trait

被引：20
|
作者：
Tripette, Julien [1 ]
Hardy-Dessources, Marie-Dominique [2 ,3 ,4 ]
Romana, Marc [2 ,3 ,4 ]
Hue, Olivier [5 ]
Diaw, Mor [6 ]
Samb, Abdoulaye [6 ]
Diop, Saliou [7 ]
Connes, Philippe [2 ,3 ,4 ,5 ]
机构：
[1] Natl Inst Hlth & Nutr, Dept Exercise Physiol, Shinjuku Ku, Tokyo 162, Japan
[2] CHU Pointe A Pitre, Hop Ricou, Inserm UMR 665, F-97157 Pointe A Pitre, Guadeloupe, France
[3] Univ Antilles Guyane, Pointe A Pitre, Guadeloupe, France
[4] PRES Sorbonne Paris Cite, Lab Excellence GR Ex Red Cell Genesis Death, Paris, France
[5] Univ Antilles Guyane, Dept Physiol, Lab ACTES EA3596, Pointe A Pitre, Guadeloupe, France
[6] UCAD, FMPOS, Lab Physiol & Explorat Fonct, Dakar, Senegal
[7] UCAD, FMPOS, Lab Hematoimmunol, Dakar, Senegal
来源：
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION | 2013年 / 55卷 / 01期
关键词：
Sickle cell trait; exercise-related sudden death; hemorheology; inflammation; vascular function; OXIDATIVE STRESS; ADHESION MOLECULES; BENIGN CONDITION; BLOOD-VISCOSITY; HEMORHEOLOGY; CHILDREN; CARRIERS; DISEASE; RISK; RHABDOMYOLYSIS;
D O I：
10.3233/CH-131687
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This review presents the epidemiological data regarding the exercise-related complication in exercising sickle cell trait carriers, and focuses on the different potential mechanisms that could be involved in these adverse events, such as hemorheological alterations, inflammation, vascular adhesion of circulating blood cells, oxidative stress and impaired nitric oxide metabolism. We also discuss the effects of different modulating factors such as vascular function, environment (hot temperature), hydration status, physical fitness, exercise intensity and genetic factors.
引用
收藏
页码：29 / 37
页数：9
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