Triterpene Glycosides from the Seeds of Dolichos lablab

被引:7
|
作者
Yokosuka, Akihito [1 ]
Takayama, Hiroki [1 ]
Mimaki, Yoshihiro [1 ]
机构
[1] Tokyo Univ Pharm & Life Sci, Dept Med Pharmacognosy, Sch Pharm, 1432-1 Horinouchi, Hachioji, Tokyo 1920392, Japan
关键词
triterpene glycoside; Dolichos lablab; Leguminosae; cytotoxic activity; MEDICINAL FOODSTUFFS; SAPONINS;
D O I
10.1248/cpb.c19-00155
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new triterpene glycosides (1 and 2), together with nine known triterpene glycosides (3-11), were isolated from the seeds of Dolichos lablab (Leguminosae). The structures of the new compounds were determined by spectroscopic analysis, including two-dimensional NMR spectroscopy, and chromatographic analysis of the hydrolyzed products. The isolated compounds did not show cytotoxicity against HL-60 human leukemia cells and HepG2 human hepatoma cells at sample concentrations of 20 mu M.
引用
收藏
页码:604 / 608
页数:5
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